New brain monitoring method may predict injury in tiniest newborns

NCT ID NCT02814383

First seen Jul 01, 2026 · Last updated Jul 01, 2026

Summary

This study investigates whether a non-invasive brain monitoring tool can predict brain injury in extremely low birth weight infants (≤1000 grams) during their first week of life. Researchers will measure brain blood flow using ultrasound and other sensors to see if changes in perfusion signal risk for conditions like intraventricular hemorrhage. The goal is to develop an early warning system that could guide care and prevent lasting damage.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could lead to a monitoring system that helps doctors detect and prevent brain injury in premature infants before it becomes irreversible.

What could go wrong

This is an observational study focused on understanding physiology, not testing a treatment. It is small (70 infants) and early-stage, so it may not directly change care.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

brain injury periventricular leukomalacia Premature Birth

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Baylor College of Medicine

    Houston, Texas, 77030, United States

  • Texas Children's Hospital

    Houston, Texas, 77030, United States

  • Texas Children's Pavilion for Women

    Houston, Texas, 77030, United States