Study probes link between transfusions and gut trouble in preterm infants

NCT ID NCT02741648

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at 324 extremely low birth weight preterm infants (≤1250 grams) to see how anemia and red blood cell transfusions affect oxygen levels in their digestive tract. Researchers used a non-invasive device to measure tissue oxygen and collected blood, urine, and stool samples. The goal was to find clues that might explain why some babies develop necrotizing enterocolitis, a serious gut condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this research could help doctors better understand why some preterm infants develop a serious gut condition called necrotizing enterocolitis after a transfusion.
What could go wrong
This is an observational study, not a treatment trial. It aims to gather information, not test a new therapy, so it will not directly change care yet.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Emory University Hospital Midtown

    Atlanta, Georgia, 30308, United States

  • Grady Memorial Hospital

    Atlanta, Georgia, 30303, United States

  • Northside Hospital - Neonatology

    Atlanta, Georgia, 30342, United States

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