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Can catching anemia months before joint surgery speed recovery?

NCT ID NCT05648942

Disease control Sponsor: Ottawa Hospital Research Institute Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 02, 2026 · Last updated Sep 03, 2026 · Updated 1 time

Summary

This trial tests whether screening for anemia at the time a patient consents to hip or knee replacement surgery, which is usually 4 to 6 months before the operation, leads to better outcomes than the standard approach of testing only 2 to 4 weeks before surgery. About 800 adults awaiting primary joint replacement will be randomly assigned to either early testing or usual care. Those found to have anemia in the early testing group will be referred to a blood optimization clinic for treatment. The study asks whether this earlier identification and treatment is feasible and whether it can reduce anemia before surgery and improve recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Point-of-care anemia testing at the time of surgery consent, followed by referral to a blood optimization clinic if anemia is found
What this could lead to
If early testing works, it could reduce post-surgery complications and help patients recover faster after joint replacement.
What could go wrong
The trial is early and focuses on feasibility, so it may not prove that early testing improves outcomes. Some patients may not follow through with treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

800 people

The number who actually took part.

Started

Jan 2023

Finished

Aug 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 18 years of age * Undergoing primary arthroplasty procedure * Willing and able to provide informed consent Exclusion Criteria: * Patients who are not eligible for assessment and optimization in the preoperative blood optimization clinic. This includes patients with end-stage renal disease (ESRD) or other renal conditions under the care of nephrologists, receiving erythropoietin treatment * Patients with known hematological malignancy or other hematological conditions which are already on some form of anemia treatment

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Conditions

The condition(s) this trial relates to.

anemia osteoarthritis, hip

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anemia Hip osteoarthritis

Contacts and locations

Locations

  • The Ottawa Hospital

    Ottawa, Ontario, K1H 8L6, Canada

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