Cataract

This study is testing a new device called Virtuoso for eye surgeries like cataract removal and vitrectomy. The goal is to make sure it is safe and works well. About 205 adults who need these surgeries will take part. The study will compare how often problems happen during surgery…

This study tests an experimental eye drop called ZOC2017217 in 40 people with age-related cataracts. Participants will use the drops twice a day for 24 weeks to see if it improves vision and lens clarity compared to a placebo. The goal is to find a non-surgical option for catarac…

This study tests a special lens implant that corrects cataracts, presbyopia (need for reading glasses), and astigmatism (blurry vision from an irregularly shaped cornea). The goal is to see if this lens stays stable in the eye and provides good vision at all distances. About 100 …

This study compares a new domestic trifocal lens (D615L) to the Zeiss AT LISA tri 839MP for people having cataract surgery. 90 adults with age-related cataracts will receive one of the two lenses and be followed for 6 months to measure vision at different distances. The goal is t…

This study tests two types of advanced lens implants (IOLs) for people having cataract surgery in both eyes. The lenses are designed to help see clearly at far, arm's length, and near distances. Researchers will check safety and how well the lenses work in 110 participants over t…

This study tests a special implant placed in the eye during vitrectomy surgery to see if it can safely slow down cataract formation. About 30 adults who need vitrectomy and already have some cataract will receive the implant. The goal is to delay cataract progression, possibly re…

This study tests a new preloaded lens delivery system for cataract surgery in 200 adults aged 40 and older. The device is designed to simplify the procedure and reduce handling of the lens. Researchers will measure how well patients see after surgery and how surgeons rate the sys…

This study tests a new type of lens implant for people having cataract surgery. The lens uses fluid to adjust focus, aiming to improve vision compared to a standard fixed-focus lens. About 175 participants will receive either the new lens or a standard one, and their vision and a…

This study follows about 500 people who already had cataract surgery with a special adjustable lens (RxSight LAL) or a standard lens. Researchers want to see how well the lens works over time, focusing on vision sharpness and correction of astigmatism. Participants just need to c…

This study tests a new type of artificial lens (enVista Beyond) for people having cataract surgery. The lens is designed to improve intermediate vision, like seeing a computer screen, while still providing good distance and near vision. About 304 adults will receive the lens in b…

This study is checking the long-term safety and performance of a special lens called the Clareon Toric IOL, which is implanted during cataract surgery to also correct astigmatism. About 129 people with cataracts and astigmatism are taking part. The main goal is to see how well th…

This study follows 23 people who received a special lens implant that slowly releases a glaucoma drug (bimatoprost) during cataract surgery. Researchers want to see if it keeps eye pressure low and vision clear for up to 7 years. The goal is to learn whether this combination devi…

This study looks at how well a new type of lens, called Clareon TruPlus, helps people see clearly at intermediate distances (like a computer screen) after cataract surgery. About 50 adults with cataracts in both eyes will get this lens and be tested 12 weeks after surgery. The go…

This study was designed to compare a tiny steroid insert (Dextenza) placed in the tear duct against standard steroid eye drops (prednisolone) after cataract surgery in people with diabetes. The goal was to see which better controls eye inflammation and swelling. However, the stud…

This study tests whether playing music through headphones for 15 minutes before cataract surgery can help reduce anxiety, pain, and improve satisfaction. Sixty adults having cataract surgery will either listen to music or wear headphones with no music. Researchers will measure st…

This study compares two ways to manage pain during cataract surgery: numbing eye drops (topical anesthesia) versus general anesthesia (being fully asleep). Researchers will follow 50 adults for up to six weeks after surgery, measuring pain, complications, and satisfaction. The go…

This study compares a new adaptive fluidics system to traditional methods during cataract surgery. The goal is to keep eye pressure stable and reduce risks. About 320 adults with lens diseases will take part. The new system adjusts fluid flow in real time to avoid sudden pressure…

This study tests whether extra support from a nurse via phone calls and text messages helps patients stick to their eye drop schedule and feel more satisfied after cataract surgery. About 128 adults having cataract surgery for the first time will be split into two groups: one get…

This study compares two types of artificial lens implants used in cataract surgery. Some patients will get a different lens in each eye, while others will get the same lens in both eyes. The goal is to see which approach gives better vision and causes fewer problems like glare, h…

This study follows 110 people who previously took part in the AREDS or AREDS2 trials to see how age-related macular degeneration (AMD) and cataracts change over time. Participants get a yearly eye exam, including vision tests and eye photos, and may give a blood sample. The goal …

This study aims to help adults aged 40 and older in Upper Manhattan get better eye care. It will offer free eye screenings at local health centers and senior centers, and provide support like scheduling appointments and transportation. The goal is to see if this extra help leads …

This study compares two methods for teaching cataract surgery to ophthalmology residents. One group learns steps in the usual order, while the other learns easier steps first. Researchers will measure how well residents perform surgery and how often complications occur. The goal …

This study tests whether a smartphone app (WHOeyes) plus a symptom questionnaire can safely replace the standard in-clinic checkup one week after cataract surgery. About 334 people aged 50–80 with uncomplicated cataracts will either use the app at home or come to the clinic. The …

This study was designed to compare two newer technologies for cataract surgery: a femtosecond laser and a special handpiece that monitors eye pressure. The goal was to see if these tools cause less damage to the cornea and use less energy than standard methods. However, the study…

This study tests a special scanning device that measures how stiff the eye's lens is in people with cataracts. Researchers want to see if this stiffness measurement matches standard cataract grading and surgery energy needed. 50 adults with cataracts will be scanned before surger…

This study is observing 500 people having cataract surgery to see how well different types of artificial lens implants (monofocal, multifocal, and toric) perform. Researchers will measure vision and patient satisfaction 3-6 months after surgery. The goal is to understand what mak…

This study follows 600 children aged 0-16 who had cataract surgery after an eye injury. Researchers will check vision, eye growth, and complications over 5-10 years to understand long-term healing and guide better care. No new treatment is tested—just careful observation of past …

This study tests whether a custom AI chatbot can help cataract patients better understand their artificial lens choices before meeting their surgeon. About 70 adults will either get standard counseling or standard counseling plus an AI explanation. The goal is to see if the AI to…

This study aimed to compare two different surgical systems for cataract removal in adults with moderate to severe cataracts. The goal was to see which system was safer and more efficient. However, the study was withdrawn before any participants were enrolled, so no results are av…

This study follows 61 people who previously used the REVISYON SDS 100 device for mild-to-moderate cataract. Researchers will check for side effects and measure vision changes over about 20 months. No new treatment is given; the goal is to see if the device stays safe and works we…

This study planned to observe different surgical approaches for children with cataracts, focusing on implant types and surgery timing. It was withdrawn before enrolling any participants, so no information was collected. The goal was to understand which strategies work best for yo…

This study offers free vision screenings to underserved adults over 40 living in affordable housing in Harlem and Washington Heights. The goal is to find eye problems like glaucoma, cataracts, and diabetic retinopathy early and connect people with follow-up care. About 749 partic…

This study looks at how well people can see up close without glasses after cataract surgery, using three different types of lens implants: the Light Adjustable Lens, the Light Adjustable Lens Plus, and a standard monofocal lens. Researchers will measure the range of near vision i…

This pilot study looks at whether metformin, a standard diabetes medicine, gets into the lens capsule of the eye and can slow the growth of lens cells that cause cataracts. Researchers will collect blood and lens tissue from 40 people with type 2 diabetes and age-related cataract…

This study was designed to check the long-term safety and performance of AcrySof IQ Vivity lens implants in people who had them in both eyes for 3 to 5 years. It was a real-world observation, not a treatment test. However, the study was withdrawn before enrolling any participants…