Carpal tunnel syndrome
MONDO:0007275Entrapment of the median nerve in the wrist that is characterized by numbness, tingling and painful movement.
Also known as: carpal tunnel syndrome, CTS, amyotrophy, thenar, of carpal origin
144 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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Could mild low-oxygen air boost nerve repair without surgery?
Disease control ENROLLING_BY_INVITATIONThis study tests whether breathing short bursts of air with slightly less oxygen can help nerves in the hand heal better after injury. The therapy is non-invasive and aims to improve hand function and reduce pain. About 80 adults with severe carpal tunnel syndrome will be enrolle…
Phase: NA • Sponsor: University of Alberta • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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Needle-Free carpal tunnel diagnosis on the horizon?
Diagnosis ENROLLING_BY_INVITATIONThis study explores whether ultrasound elastography, a non-invasive imaging technique, can accurately diagnose carpal tunnel syndrome (CTS) without the need for painful needle-based nerve tests. Researchers will enroll 80 participants—some with CTS and some healthy volunteers—to …
Sponsor: Da Nang Family General Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 11:04 UTC
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Ultrasound-Delivered pain gel shows promise for carpal tunnel sufferers
Symptom relief OngoingThis study tests whether a pain-relief gel (pregabalin) delivered through the skin using ultrasound can reduce pain and improve hand function in people with carpal tunnel syndrome. The treatment is given four times a week for a month, and compared to standard ultrasound therapy w…
Phase: NA • Sponsor: University of Faisalabad • Aim: Symptom relief
Last updated Jun 27, 2026 13:04 UTC
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Can learning about pain or using tape ease carpal tunnel symptoms?
Symptom relief OngoingThis study tests two simple treatments for mild to moderate carpal tunnel syndrome: pain neuroscience education (learning how the brain processes pain) and kinesio taping (applying elastic tape to the wrist). Sixty adults aged 18 to 60 with symptoms for at least 3 months will rec…
Phase: NA • Sponsor: Middle East University • Aim: Symptom relief
Last updated Jun 27, 2026 12:10 UTC
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Sugar water injection may ease carpal tunnel pain
Symptom relief OngoingThis study tests whether injecting a 5% dextrose (sugar water) solution around the nerve in the wrist can reduce pain and improve hand function in people with mild to moderate carpal tunnel syndrome. About 96 adults who haven't gotten better with standard care will receive the in…
Phase: NA • Sponsor: Antalya Training and Research Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:06 UTC
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Could a simple tourniquet change cut Post-Surgery pain and opioid use?
Symptom relief OngoingThis study tests whether using a lower-pressure tourniquet during orthopedic surgeries can reduce pain and the need for opioid painkillers afterward. Standard tourniquets use high pressure, which can cause muscle weakness and pain. The experimental device sets pressure based on t…
Phase: NA • Sponsor: The Methodist Hospital Research Institute • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Mud vs. wax: which soothes carpal tunnel pain best?
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether warm paraffin wax baths or mud therapy (peloidotherapy) can reduce pain and improve hand function in people with mild to moderate carpal tunnel syndrome. Ninety adults will be split into three groups: one gets mud plus home exercises, another gets wax plu…
Phase: NA • Sponsor: Konya Beyhekim Training and Research Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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Carpal tunnel showdown: shots or knife?
Symptom relief OngoingThis study looks at two treatment plans for carpal tunnel syndrome, which causes hand numbness and pain. One plan starts with up to two steroid injections, then offers surgery if needed. The other plan goes straight to surgery. About 258 adults with mild to moderate symptoms will…
Phase: PHASE4 • Sponsor: Diakonhjemmet Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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Could a short steroid course after surgery reduce pain and nausea?
Symptom relief ENROLLING_BY_INVITATIONThis study looks at whether a 6-day course of oral steroids after orthopedic surgery can help reduce pain, nausea, and improve movement. About 500 adults having common surgeries like joint replacement or fracture repair will be randomly assigned to receive either standard care or…
Phase: PHASE4 • Sponsor: Emory University • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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Could a 12-minute electrical zap ease your numb fingers?
Symptom relief OngoingThis study looks at whether a type of electrical current called diadynamic current can reduce pain and improve hand function in people with carpal tunnel syndrome. About 80 adults with mild to moderate carpal tunnel syndrome will receive this therapy along with standard care like…
Phase: NA • Sponsor: Duzce University • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Could body fat ease carpal tunnel pain? new study investigates
Symptom relief TerminatedThis study tests whether injecting a patient's own fat (lipografting) into the wrist can improve symptoms of mild to moderate carpal tunnel syndrome better than standard steroid injections. The fat is thought to reduce scarring and help nerves glide more freely. The trial plans t…
Phase: EARLY_PHASE1 • Sponsor: Columbia University • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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Baking soda in numbing shots could ease carpal tunnel surgery pain
Symptom relief OngoingThis study tests whether adding sodium bicarbonate (baking soda) to the local anesthetic used during carpal tunnel release surgery reduces the pain of the injection itself. 116 adults with carpal tunnel syndrome will be randomly assigned to receive either buffered or standard ane…
Phase: NA • Sponsor: Kuopio University Hospital • Aim: Symptom relief
Last updated Jun 26, 2026 18:40 UTC
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Which stitch leaves a better scar after carpal tunnel surgery?
Symptom relief OngoingThis study compares two common types of stitches used to close the wound after carpal tunnel release surgery: absorbable stitches that dissolve on their own and non-absorbable stitches that need to be removed. About 116 patients will be randomly assigned to one stitch type, and t…
Phase: NA • Sponsor: Kuopio University Hospital • Aim: Symptom relief
Last updated Jun 26, 2026 18:34 UTC
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Zapped nerves: study planned to boost recovery after surgery — but never started
Knowledge-focused TerminatedThis study was designed to see if giving a short, mild electrical stimulation to compressed nerves during surgery could speed up recovery of strength and function. It planned to include people with nerve compression in the spine or limbs who were already scheduled for decompressi…
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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Med student stress may be tied to wrist pain, new study suggests
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at whether anxiety and depression are connected to carpal tunnel syndrome in medical students. Researchers will measure the median nerve in the wrist and check students' anxiety and depression levels using questionnaires. The goal is to see if there is a link bet…
Sponsor: University of Ioannina • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Decision aids may ease patient uncertainty in hand surgery
Knowledge-focused TerminatedThis study tests whether giving patients with hand problems like carpal tunnel syndrome or trigger finger a decision aid—a booklet with clear information about their condition and treatment options—helps them feel more satisfied and less conflicted about their choices. About 126 …
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Can a simple scale accurately measure hand problems in carpal tunnel syndrome?
Knowledge-focused ENROLLING_BY_INVITATIONThis study is checking whether a questionnaire called the MAP-Hand scale is a valid and reliable way to measure hand activity in people with carpal tunnel syndrome. Researchers will enroll 180 adults with mild or moderate carpal tunnel syndrome and compare their scale results to …
Sponsor: Kirsehir Ahi Evran Universitesi • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Stitch showdown: which suture leaves a better scar after hand surgery?
Knowledge-focused TerminatedThis study aimed to see if using stitches that dissolve (absorbable) or stitches that need removal (non-absorbable) leads to better scar appearance and patient satisfaction after carpal tunnel or trigger finger surgery. It was planned for adults having these common hand surgeries…
Phase: NA • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Thousands tracked after carpal tunnel surgery: does new device deliver?
Knowledge-focused OngoingThis study is tracking 2000 adults with carpal tunnel syndrome who are having surgery to release the nerve. The surgery uses a special device called UltraGuideCTR, which is guided by ultrasound. Researchers are collecting real-world data on symptoms and hand function for up to 24…
Sponsor: Sonex Health, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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New ultrasound could better track carpal tunnel recovery
Knowledge-focused ENROLLING_BY_INVITATIONThis study tests a new ultrasound technique called shear wave elastography to measure stiffness in the wrist nerves and tissues of people with carpal tunnel syndrome. Researchers will compare these measurements with standard tests before and after treatment (surgery or steroid in…
Phase: NA • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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New pathway aims to cut wait times for carpal tunnel patients
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at whether a new care pathway can shorten wait times for people with carpal tunnel syndrome. Researchers will compare wait times before and after the pathway is put in place. About 200 adults will take part and fill out a short satisfaction survey.
Sponsor: University of British Columbia • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC