Baking soda in numbing shots could ease carpal tunnel surgery pain
NCT ID NCT05328180
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests whether adding sodium bicarbonate (baking soda) to the local anesthetic used during carpal tunnel release surgery reduces the pain of the injection itself. 116 adults with carpal tunnel syndrome will be randomly assigned to receive either buffered or standard anesthetic. The main goal is to see if the buffered solution causes less burning, pressure, and overall pain during the injection.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
sodium bicarbonate added to local anesthetic (lidocaine and bupivacaine with adrenaline)
What this could lead to
If it works, this could make the numbing injection less painful for people having carpal tunnel surgery.
What could go wrong
This is a small, early-stage trial (116 people) testing a minor change to a standard procedure. Even if it reduces injection pain, the effect may be small or not apply to everyone.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Kuopio University hospital, Department of Orthopaedics, Traumatology and Hand Surgery
Kuopio, Northern Savonia, 70029, Finland