Bone fracture
MONDO:0005315Breaks in bones.
Also known as: fracture, fracture of bone, fracture(s)
733 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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Shoulder implant under review: will it last 10 years?
Disease control TerminatedThis study looked at a shoulder implant used to treat pain and joint problems from conditions like arthritis, fractures, and rotator cuff tears. It involved 67 adults who received the implant and tracked how long it lasted and any side effects over 10 years. The goal was to confi…
Sponsor: Zimmer Biomet • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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New spinal implant studied for osteoporosis fractures
Disease control TerminatedThis study tested a new device called the Vertebral Implant PEEK (VIP) for people with spine fractures due to osteoporosis. The goal was to see if the implant is safe and helps repair the broken bone. The study included 23 adults aged 50 and older with recent fractures that did n…
Phase: NA • Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Disease control
Last updated Jun 27, 2026 12:39 UTC
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New cement promises stronger healing for spine fractures
Disease control TerminatedThis study tested a special cement that mimics natural bone to repair broken vertebrae in adults aged 18 to 65. The cement is designed to be absorbed by the body and replaced with new bone over time. Only 4 people took part before the study was stopped early. The goal was to see …
Phase: PHASE2 • Sponsor: University Hospital, Bordeaux • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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New bone graft shows promise for healing leg breaks
Disease control TerminatedThis study tested a new bone grafting material called SurgiFill™ in 60 people with broken thigh or shin bones. The goal was to see if it helps bones heal faster and safely. The study was stopped early, so results are limited.
Phase: NA • Sponsor: Cellontech Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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New curved rod shows promise for tough pelvic breaks
Disease control TerminatedThis study tested a special curved rod implant designed to fix broken pelvic and hip socket bones. It included 53 adults who had already received the implant. Researchers tracked whether patients needed more surgeries and how well they could move and bear weight afterward.
Sponsor: CurvaFix, Inc. • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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New shoulder implant tested for severe arthritis – but study halted early
Disease control TerminatedThis study looked at the TITAN Reverse Shoulder System, a device used to replace the shoulder joint in people with severe arthritis and a torn rotator cuff. The goal was to see if it relieves pain and improves movement. About 151 people were planned to take part, but the study wa…
Sponsor: Smith & Nephew, Inc. • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Hip fracture pain study halted early – results uncertain
Symptom relief TerminatedThis study compared two common nerve block techniques for pain relief after hip fracture surgery: femoral nerve block and suprainguinal fascia iliaca block. Only 17 adults participated before the trial was terminated early. The goal was to see which block reduces pain and the nee…
Phase: NA • Sponsor: University of Alberta • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Steroid injection for broken wrist: did it help?
Symptom relief TerminatedThis study looked at whether a steroid (glucocorticoid) injection given around the time of surgery could improve wrist movement and reduce pain in adults with a broken wrist. About 38 people were planned to take part, but the study was stopped early. The goal was to see if the in…
Phase: PHASE4 • Sponsor: C. Liam Dwyer • Aim: Symptom relief
Last updated Jun 27, 2026 12:25 UTC
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Can Over-the-Counter meds replace opioids for Kids' elbow pain?
Symptom relief TerminatedThis study looked at two common ways to manage pain in children after elbow fracture surgery: opioids versus over-the-counter medications like ibuprofen and acetaminophen. The goal was to see if non-opioid options work just as well, reducing the need for opioid prescriptions. The…
Phase: PHASE4 • Sponsor: Baylor College of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 09:03 UTC
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Protein powder fails to prove recovery boost in tiny hip fracture trial
Symptom relief TerminatedThis small trial tested whether adding a special protein-and-vitamin powder to the diet could help older adults walk better after surgery for a broken femur. Only 20 people took part, and the study was stopped early. The main goal was to see if the supplement improved walking spe…
Phase: NA • Sponsor: Barichella Michela • Aim: Symptom relief
Last updated Jun 26, 2026 13:52 UTC
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Real-world review of bone-fixation devices aims to confirm their safety and performance.
Knowledge-focused TerminatedThis study looks back at medical records of up to 118 patients in Italy who had surgery using the GALAXY FIXATION system or other Orthofix devices to stabilize fractures of the long bones (like the thigh or shin) or the pelvis. The goal is to see how well these devices hold the b…
Sponsor: Orthofix s.r.l. • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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New muscle measurement method tested in seniors
Knowledge-focused TerminatedThis study tested a new technique that uses a special form of creatine (deuterated creatine) to measure muscle mass more directly and accurately in older adults. The goal was to see if this method works well in both healthy older adults and those recovering from a hip fracture. T…
Phase: NA • Sponsor: University Hospital, Toulouse • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Smell test after brain surgery: what surgeons learned
Knowledge-focused TerminatedThis study looked at how a person's sense of smell changes after endoscopic endonasal skull base surgery, a procedure done through the nose to remove tumors or other abnormalities. Researchers measured smell using a simple identification test in 50 patients before and after surge…
Sponsor: Ricardo L. Carrau, MD • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Ankle fracture study: does early washing protect joints?
Knowledge-focused TerminatedThis study looked at whether washing out the ankle joint with salt water within 48 hours of a fracture can lower inflammation and prevent cartilage breakdown. Researchers measured chemicals in the joint fluid of 41 adults before and after surgery. The goal was to see if early cle…
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Bone-Lengthening nail study ends early after just one patient
Knowledge-focused TerminatedThis study looked at the safety and performance of the Fitbone Transport and Lengthening Nail, a device implanted in the bone to help repair large bone gaps or correct leg length differences. Only one person took part before the study was stopped early, so the results are very li…
Sponsor: Orthofix Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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Tiny study on Kids' arm casts halted before any answers
Knowledge-focused TerminatedThis study aimed to see if a cast that keeps the elbow straight or bent works better for certain forearm fractures in children. Only 3 children joined before the study was stopped early. Because of this, we cannot say which cast is better.
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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10-Year hip implant study ends early – what we know
Knowledge-focused TerminatedThis study followed 10 people who received an ESOP 2 hip stem during total hip replacement. Researchers wanted to see how safe and effective the device was over 10 years in real-life use. The study was stopped early, so the full long-term picture is incomplete.
Sponsor: FH ORTHO • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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New hip implant put to the test: will it stay put?
Knowledge-focused TerminatedThis study looked at a specific hip implant shell (the Pinnacle Acetabular Shell) used in total hip replacement. Researchers wanted to see how much the implant moved (migrated) over two years using a special X-ray technique called RSA. They also tracked how patients felt and func…
Phase: NA • Sponsor: DePuy Orthopaedics • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC