New shoulder implant tested for severe arthritis – but study halted early
NCT ID NCT02204228
First seen Oct 31, 2025 · Last updated Jun 23, 2026 · Updated 26 times
Summary
This study looked at the TITAN Reverse Shoulder System, a device used to replace the shoulder joint in people with severe arthritis and a torn rotator cuff. The goal was to see if it relieves pain and improves movement. About 151 people were planned to take part, but the study was stopped early, so the full results are not available.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Active Orthopedics
Glen Ridge, New Jersey, 07028, United States
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Barts Health NHS Trust
London, United Kingdom
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Clinique Bizet
Paris, France
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Hospital de Manacor - Llevant
Manacor, 07500, Spain
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Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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Johns Hopkins University
Columbia, Maryland, 21044, United States
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Mississipi Bone and Joint Clinic
Starkville, Mississippi, 39759, United States
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The Rothman Institute
Philadelphia, Pennsylvania, 19107, United States
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University of Florida
Gainesville, Florida, 32607, United States
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Westphal Orthopaedics
Lancaster, Pennsylvania, 17601, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
TITAN™ Reverse Shoulder System (a shoulder replacement device)
What this could lead to
If successful, this device could provide a reliable option for pain relief and improved shoulder function in patients with severe arthritis and a torn rotator cuff.
What could go wrong
The study was terminated early, so results are limited. As with any surgery, risks include infection, implant loosening, or nerve injury.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.