New shoulder implant tested for severe arthritis – but study halted early

NCT ID NCT02204228

Terminated Disease control Sponsor: Smith & Nephew, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at the TITAN Reverse Shoulder System, a device used to replace the shoulder joint in people with severe arthritis and a torn rotator cuff. The goal was to see if it relieves pain and improves movement. About 151 people were planned to take part, but the study was stopped early, so the full results are not available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: TITAN™ Reverse Shoulder System (a shoulder replacement device)
What this could lead to: If successful, this device could provide a reliable option for pain relief and improved shoulder function in patients with severe arthritis and a torn rotator cuff.
What could go wrong: The study was terminated early, so results are limited. As with any surgery, risks include infection, implant loosening, or nerve injury.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

bone fracture osteoarthritis osteonecrosis rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEOARTHRITIS OF THE SHOULDER

Contacts and locations

Locations

Active Orthopedics

Glen Ridge, New Jersey, 07028, United States
Barts Health NHS Trust

London, United Kingdom
Clinique Bizet

Paris, France
Hospital de Manacor - Llevant

Manacor, 07500, Spain
Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States
Johns Hopkins University

Columbia, Maryland, 21044, United States
Mississipi Bone and Joint Clinic

Starkville, Mississippi, 39759, United States
The Rothman Institute

Philadelphia, Pennsylvania, 19107, United States
University of Florida

Gainesville, Florida, 32607, United States
Westphal Orthopaedics

Lancaster, Pennsylvania, 17601, United States

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