Platelet-Rich plasma may beat steroids for shoulder arthritis pain

NCT ID NCT05160441

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether a shot of platelet-rich plasma (PRP) from a person's own blood works better than a common steroid shot for shoulder arthritis pain. Fifty adults with mild to moderate shoulder osteoarthritis received either a PRP or steroid injection. Researchers measured pain, function, and quality of life over time to see which treatment offers better relief.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Platelet-rich plasma (PRP) injection and corticosteroid injection

What this could lead to

If PRP works better than steroids, it could offer a longer-lasting, safer option for easing shoulder arthritis pain without surgery.

What could go wrong

This is a small, completed Phase 3 trial with only 50 participants. PRP may not prove more effective than steroids, and results may not apply to everyone with shoulder arthritis.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

familial pityriasis rubra pilaris osteoarthritis Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Walter Reed National Military Medical Center

    Bethesda, Maryland, 20889, United States