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Light-Activated implant could mend Cancer-Weakened bones without major surgery

NCT ID NCT02373904

Terminated Disease control Sponsor: IlluminOss Medical, Inc. Source: ClinicalTrials.gov ↗

First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time

Summary

This study tests a device called the Photodynamic Bone Stabilization System for treating painful fractures or impending fractures in the upper arm bone (humerus) caused by cancer that has spread to the bone. The device is inserted into the bone and hardened with light to provide stability. The trial measures whether it reduces pain and improves daily function in adults with metastatic bone disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a photodynamic bone stabilization system (a device that is inserted into the bone and hardened with light to stabilize fractures)
What this could lead to
If successful, this device could offer a less invasive way to stabilize arm bones weakened by cancer, reducing pain and helping people regain daily function.
What could go wrong
This is a small, early study with only 14 participants, so results may not apply to everyone. The device may not work for all fracture types or could have complications like infection or device failure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

humerus fracture metastatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HUMERUS PATHOLOGICAL FRACTURE

Contacts and locations

Locations

  • Johannes Wesling Klinikum Minden

    Minden, 32429, Germany

  • Lahn-Dill Kliniken

    Wetzlar, 35578, Germany

  • Medical Center Leeuwarden

    Leeuwarden, 8934 AD, Netherlands

  • Medical University of Vienna

    Vienna, 1090, Austria

  • Medisch Spectrum Twente

    Enschede, 7513 ER, Netherlands

  • St. Vinzenz-Hospital GmbH

    Cologne, D-50733, Germany

More trials for these conditions

Other studies related to the condition(s) this trial covers.