Hip replacement vs. metal rods: which surgery is better for bone cancer?
NCT ID NCT06863129
First seen Jun 27, 2026 · Last updated Jul 09, 2026 · Updated 2 times
Summary
This study looks at two types of hip surgery for people whose cancer has spread to the hip bone. One surgery removes the damaged bone and replaces it with an artificial joint. The other uses metal rods and plates to hold the bone together. The goal is to see which surgery leads to fewer problems, better physical function, and more time at home. About 334 adults with a life expectancy of at least 6 months will take part and be followed for one year.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 334 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Feb 2025
- Expected to finish
-
Jun 2030
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Life expectancy of at least 6 months * Lesions in the proximal femur (femoral neck, intertrochanteric region, subtrochanteric region, and combinations thereof) * Low or intermediate risk for perioperative morbidity and/or mortality * No more than 75% and no less than 25% bone loss * Mutual (patient and physician) decision to perform surgical management of an impending or realized pathologic fracture due to MBD of the proximal has been made. Exclusion Criteria: * Lesions isolated to the femoral neck * Lesion with any femoral head involvement * High risk for perioperative morbidity and/or mortality * Multidisciplinary decision that resection of the entire lesion would be indicated
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Metastatic bone disease are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
7 sites in 4 countries. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Albany Medical Center
ACTIVE_NOT_RECRUITINGAlbany, New York, 12206, United States
-
Foothills Medical Centre
NOT_YET_RECRUITINGCalgary, Alberta, Canada
-
Good Samaritan Regional Medical Center
WITHDRAWNCorvallis, Oregon, 97330, United States
-
Hospital de Clínicas de Porto Alegre
RECRUITINGPorto Alegre, Rio Grande do Sul, 90450050, Brazil
-
Hôpital Maisonneuve-Rosemont
WITHDRAWNMontreal, Quebec, H1T 2M4, Canada
-
McGill University Health Centre
ACTIVE_NOT_RECRUITINGMontreal, Quebec, H4A 3J1, Canada
-
Medical University Graz
RECRUITINGGraz, Austria
-
Mount Sinai Hospital
ACTIVE_NOT_RECRUITINGToronto, Ontario, M5G 1X5, Canada
-
Oregon Health and Science University Hospital
RECRUITINGPortland, Oregon, 97239, United States
-
Parkview Packnett Family Cancer Institute
RECRUITINGFort Wayne, Indiana, 46845, United States
-
University of Cincinnati Medical Center
RECRUITINGCincinnati, Ohio, 45219, United States
-
University of Colorado Hospital
RECRUITINGAurora, Colorado, 80045, United States
-
University of Maryland Medical Center
ACTIVE_NOT_RECRUITINGBaltimore, Maryland, 21201, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Light-Activated implant could mend Cancer-Weakened bones without major surgery
- Can your smartphone help fight cancer? new study aims to find out
- Zapping pain away: new device could help kids with cancer ditch pain pills
- Smartwatches could predict complications in bone cancer patients
- New pelvic implant aims to ease pain and restore mobility in fragile patients