Allergic disease

This large study aims to create a digital screening and management system for adults with asthma and allergies. Nearly 10,000 participants will use a smartphone platform to track symptoms and receive guidance on three non-drug strategies: avoiding allergens (like dust mites), inc…

This trial evaluates whether a blood test called Flow CAST® can accurately identify peanut allergy. Researchers will compare results from people with peanut allergy, people with other allergies, and healthy controls. The goal is to see if this test can reliably distinguish those …

This study tests whether AI-powered decision trees can help general practitioners better diagnose and manage allergies. About 600 patients with suspected allergies will be enrolled, and doctors will use an app that suggests next steps based on symptoms. The goal is to see if this…

This study will check if a new physical exam called Said's test can accurately diagnose biceps tendon injuries in the shoulder. Researchers will test 144 adults, including those with shoulder injuries and healthy volunteers. Two doctors will perform the new test and standard test…

This study aims to validate an Italian version of a widely used questionnaire for screening periodontitis (gum disease). Researchers will also develop an enhanced version with additional questions and test how accurately it identifies people with the condition. About 495 adults a…

This study tests a new radioactive imaging agent called 68Ga-SFB6-ZN01, which is designed to attach to a protein found on many cancer cells. 98 adults with confirmed or suspected cancer will receive a single injection of the agent and then have a PET/CT scan. The goal is to see i…

This study aims to find the best concentration of Blomia tropicalis (a type of dust mite) extract for allergy skin testing. About 30 adults with known dust mite allergies will receive small pricks with different extract strengths to see which causes a reaction similar to a standa…

This study tests whether a specific mix of probiotics can prevent allergies in breastfed infants who received antibiotics within their first month of life. Researchers will give the probiotic or a placebo to 400 babies and track allergy development, gut bacteria changes, and grow…

This study tests whether a special package of bathing, skincare, and allergen exposure advice can prevent food allergies in infants at risk. Researchers will compare the package to usual care in 64 newborns. Parents will follow recommendations like delaying the first bath and avo…

This study will test whether a partially hydrolyzed whey protein formula can help ease mild allergy symptoms in infants. About 160 babies with mild skin, stomach, or breathing issues will be randomly assigned to get either the special formula or a standard cow's milk formula. Res…

This early-stage study tests a new injection called JYB1904 in 12 teenagers aged 12-17 with allergies like hay fever, asthma, or food allergies. The main goal is to see if the drug is safe and how the body processes it. Participants will be closely monitored for side effects and …

This study looks at whether breast cancer patients can safely stop taking allergy-preventing medications before weekly paclitaxel after two doses without a reaction. Researchers want to see if stopping these drugs improves quality of life, since they can cause side effects like i…

This study tests whether giving a steroid and antihistamine just 1 hour before a CT scan is as safe as the standard 4-hour premedication for people with contrast allergies. It involves 540 emergency department adults who need a CT for a serious condition. If successful, it could …

Researchers at a French hospital are following 100 children aged 6 months to 17 years who are allergic to legumes other than peanut, such as peas, chickpeas, lentils, soy, lupin, and fava beans. The study tracks which legumes cause reactions, how old children are at first symptom…

This study tests whether a skin test can predict allergic reactions to the chemotherapy drug oxaliplatin. About 380 cancer patients will receive a tiny amount of oxaliplatin under the skin before their regular treatment. Researchers will check if the skin test results match who a…

This study looks at how often people develop allergic skin reactions to two different wound dressings used after open shoulder surgery: one made from silk protein and another from a medical glue mesh. About 350 adults having shoulder surgery will be randomly assigned to one dress…

This study monitors 1,500 adults with breast cancer who receive LUMISIGHT during lumpectomy surgery. Researchers will track how often serious allergic reactions occur within 60 minutes of injection. No new drug is being tested; the goal is to better understand the safety of this …

This study in Côte d'Ivoire tests whether giving mothers a cash reward for breastfeeding until their child is 24 months old increases breastfeeding rates and improves child and maternal health. About 1,040 mothers will either receive the cash incentive or just educational materia…

This study looks at whether premature infants who had necrotizing enterocolitis (NEC) are more likely to develop allergies by age 2. Researchers will compare skin prick test results between 130 infants with and without NEC. The goal is to understand if NEC affects later allergy d…

This study tests a new program designed to help middle school students (ages 11-13) develop a sense of responsibility toward climate change. The program is based on two well-known theories about how people form beliefs and make decisions. Researchers will measure changes in stude…

Human seminal plasma allergy is a rare condition causing pain and inflammation after unprotected sex, but its impact on quality of life is poorly understood. This study will enroll 20 women treated at Angers University Hospital to compare standard quality-of-life questionnaires a…

This study follows 100 adults who had an allergic reaction to contrast media (dye used in CT scans and other imaging) to see if the allergy persists over time. Participants will undergo repeat skin testing to check for ongoing sensitivity. The goal is to understand how long the a…

Healthspan Connect is a new research programme aiming to understand what helps people stay healthy as they age. It will recruit 100,000 participants aged 12 and older across the UK, using digital tools and home-based sample collection. The study will explore how lifestyle, enviro…