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127005 trials found · Page 4775 of 6351
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More frequent blood pressure checks during surgery could save kidneys
Knowledge-focused By invitation onlyAround 300 million surgical operations are performed globally, and of these, 40 to 50 million are performed in the USA. The perioperative period is characterized by hemodynamic instability and, most importantly, hypotension. Intraoperative hypotension is frequent, and the inciden…
Sponsor: Konya City Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Nerve block or IV drip: which helps breast cancer patients recover better?
Symptom relief CompletedThe erector spinae plane block (ESPB) is gaining popularity as a regional anesthetic technique for major breast cancer surgery. Although there is controversy about its mechanism of action, emerging evidence suggests that clinical analgesia observed after ESPB in breast surgery ma…
Sponsor: Chinese University of Hong Kong • Aim: Symptom relief
Last updated Jun 26, 2026 15:18 UTC
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New foam method may improve varicose vein treatment
Disease control CompletedThis clinical trial aims to assess the efficacy and safety of the SALFOAM 3% method, which involves saline wash, polidocanol 3% foam injection, and extrinsic compression using Lidstop®, in comparison with the conventional Tessari method for the treatment of lower limb varicose ve…
Sponsor: Lidiane Rocha • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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Does gender change how shoulder pain feels? new study investigates
Knowledge-focused By invitation onlyThis study aimed to investigate the effects of gender on pain, functionality, range of motion, disability level and position sense parameters in patients with subacromial shoulder pain.
Sponsor: Kirsehir Ahi Evran Universitesi • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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Massive blood disorder registry aims to transform care
Knowledge-focused Recruiting nowThe Hemophilia Treatment Center (HTC) where you receive care is working with The American Thrombosis and Hemostasis Network (ATHN) to look at the quality of life of people with blood disorders and problems. Doctors, scientists, policymakers, and other health care providers need …
Sponsor: American Thrombosis and Hemostasis Network • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Tiny study aims to unlock secrets of radiation lung damage
Knowledge-focused Recruiting nowPatients with signs of radiation induced lung inflammation, who are referred for a clinical bronchoscopy for investigation, will have a sample sent for single cell sequencing. This is a novel technique which allows for identification of which cells are present and what they are d…
Sponsor: NHS Lothian • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Patch made from placenta tested for diabetic foot ulcers – trial stopped early
Disease control Stopped earlyThis randomized controlled study evaluates the adjuvant use of Amnio-Maxx in patients with diabetic foot ulcers
Sponsor: Capsicure, LLC • Aim: Disease control
Last updated Jun 27, 2026 12:38 UTC
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Skin graft trial for diabetic foot ulcers halted early
Disease control Stopped earlyThis randomized controlled study evaluates the adjuvant use of Derm-Maxx in patients with diabetic foot ulcers
Sponsor: Capsicure, LLC • Aim: Disease control
Last updated Jun 27, 2026 12:39 UTC
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CBD shows promise for alcohol use disorder in early trial
Disease control Stopped earlyThe non-psychotomimetic cannabis compound cannabidiol (CBD) has been found effective for reducing alcohol drinking in mice. Moreover, other experimental studies have found that CBD reduced alcohol-induced steatosis in the liver, and reduced alcohol-related injury in the brain. De…
Phase 2 • Sponsor: Hôpital le Vinatier • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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Paraffin or shockwaves: which eases carpal tunnel pain best?
Symptom relief Recruiting nowThe study plans to include a total of 60 patients diagnosed with carpal tunnel syndrome. Patients will be divided into two groups according to the treatment they receive. One group will receive only paraffin treatment, while the other group will receive only ESWT treatment. ESWT …
Sponsor: Emre Şenocak • Aim: Symptom relief
Last updated Jun 26, 2026 16:40 UTC
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Grape extract gummies vs capsules: which delivers more health-boosting flavanols?
Knowledge-focused CompletedPolyphenols are a group of naturally occurring compounds found in cocoa, teas, and grape seed extracts (GSE) that have been linked to various health benefits. This study will provide a greater insight into the relationship between polyphenol consumption and health, and could be u…
Sponsor: University of Ulster • Aim: Knowledge-focused
Last updated Jul 03, 2026 00:00 UTC
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Boccia game boosts arm muscle in stroke patients, small study finds
Symptom relief CompletedThis study investigates whether adding Boccia exercises to conventional rehabilitation improves upper extremity muscle thickness and grip strength in individuals with hemiparesis following stroke. The research aims to determine if Boccia training can enhance muscle morphology and…
Sponsor: Bayburt University • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Cash for cuddles: study tests if money helps preemie moms visit more
Knowledge-focused Recruiting nowPreterm birth is a leading cause of childhood mortality and developmental disabilities. Socioeconomic disparities in the incidence of preterm birth and morbidities, mortality, and quality of care for preterm infants persist. An important predictor of the long-term consequences of…
Sponsor: University of Massachusetts, Worcester • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Teens with tics needed for landmark study on hidden symptoms
Knowledge-focused Recruiting nowIndividuals with tic disorders have lower quality of life, sensory and movement difficulties, and poorer mental, social, and physical health compared to the general population. Current clinical care for individuals with tic disorders is limited: no interventions are proven to pre…
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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JointIQ supplement shows promise for active adults with knee discomfort
Symptom relief CompletedThis study is a randomized, double-blind, placebo-controlled clinical trial designed to evaluate the effects of astragaloside supplementation on joint discomfort in healthy adults. The primary goal is to determine if daily intake of astragaloside can improve knee joint function a…
Sponsor: Chung Shan Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 09:01 UTC
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Gene test may guide breast cancer treatment decisions
Knowledge-focused Recruiting nowTo prospectively evaluate the impact of HER2DX on the decision-making processes of the treating physicians and especially among the routine multidisciplinary tumour board, in defining type and setting of systemic therapy administration in patients with stage I-III HER2+ BC, and t…
Sponsor: European Institute of Oncology • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Can what you eat change your IBD outcome? new study investigates
Knowledge-focused Recruiting nowThe goal of this observational study is to demonstrate that nutritional status and body composition have an impact on clinical outcomes in inflammatory bowel disease (IBD). The main objectives are: 1. To compare the detection rates of undernutrition between a range of nutrition…
Sponsor: Barts & The London NHS Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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Could a common cholesterol drug ease pancreatitis pain?
Symptom relief Recruiting nowThe purpose of this pilot study to examine the feasibility and acceptability of simvastatin in adults with Recurrent Acute Pancreatitis (RAP) and Chronic Pancreatitis (CP).
Early phase 1 • Sponsor: Cedars-Sinai Medical Center • Aim: Symptom relief
Last updated Aug 07, 2026 00:00 UTC
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New study peers inside lungs during Clot-Busting procedure
Knowledge-focused Recruiting nowPatients with end-stage renal disease (ESRD) often require arteriovenous grafts (AVG) for hemodialysis. AVG thrombosis is a common complication, usually managed by percutaneous transluminal angioplasty (PTA) to restore blood flow. PTA achieves patency by balloon-mediated compress…
Sponsor: First Affiliated Hospital of Wannan Medical College • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Liver health may change how drug KP-001 works in the body
Knowledge-focused CompletedThis is a phase 1, open-label, non-randomized, parallel-group, single-dose study to assess the effect of hepatic impairment (assessed by the criteria of the Child-Pugh scale) on the pharmacokinetics (PK) and safety of KP-001 in adult male and non-childbearing potential female par…
Phase 1 • Sponsor: Kaken Pharmaceutical • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC