Gene test may guide breast cancer treatment decisions

NCT ID NCT06723990

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a genetic test called HER2DX can help doctors decide on the best treatment for people with early-stage HER2-positive breast cancer. The study will enroll 60 patients and observe how often the test results change the treatment plan recommended by a team of specialists. The goal is to see if the test improves confidence in treatment choices, not to directly test a new drug.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
HER2DX genetic test
What this could lead to
If successful, this could show that a genetic test helps doctors personalize treatment for HER2+ breast cancer, potentially improving outcomes and reducing unnecessary side effects.
What could go wrong
This is a small, observational study (60 people) at one center. It only measures if doctors change their decisions, not if those changes actually improve patient health. The test may not be widely adopted or beneficial.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Istituto Europeo di Oncologia

    RECRUITING

    Milan, Italy, Italy

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