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127005 trials found · Page 4545 of 6351
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Vitamin D3 shows promise for immune support in HIV patients
Disease control CompletedThis study aims to evaluate the effect of Vitamin D3 supplementation on inflammatory markers and immune status in patients with HIV who are receiving antiretroviral therapy. Participants will receive Vitamin D3 supplementation for 3 months. Outcomes including Interleukin-6 levels…
Sponsor: Universitas Sebelas Maret • Aim: Disease control
Last updated Jul 17, 2026 00:00 UTC
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Which rinse hurts less? study tests root canal irrigation methods
Symptom relief CompletedThe aim of this study is to evaluate the effect of different irrigation activation methods used during endodontic treatment on postoperative pain in teeth with periapical lesions, allowing us to clinically determine which agitation technique causes less postoperative pain.
Sponsor: Akdeniz University • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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New study aims to better classify lung tumors with air pockets
Knowledge-focused Recruiting nowThe goal of this observational study is to determine the most accurate tumor size measurement method for T-staging and prognostic assessment in lung cancer with cystic airspaces (LCCA). The main questions it aims to answer are: * What is the optimal T-staging approach for accura…
Sponsor: Central South University • Aim: Knowledge-focused
Last updated Sep 06, 2026 00:00 UTC
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Migraine Sufferers' neck function under the microscope
Knowledge-focused CompletedThe aim of this study is to compare cervical spinal stability, cervical proprioception, and body awareness in individuals with migraine and healthy controls, and to examine the relationship between these parameters. Hypotheses of the Study: H1: Cervical spinal stability differs…
Sponsor: Hacettepe University • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:45 UTC
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Mass kidney screening in brazil reveals hidden disease burden
Knowledge-focused CompletedThis is a multicenter cross-sectional study will randomly screen kidney function in adult patients with known risk factors for chronic kidney disease (CKD) within the Brazilian general population. Kidney function will be assessed using a point-of-care creatinine test at local hea…
Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Neck moves during game keep Pitchers' shoulders in top shape
Symptom relief CompletedThe goal of this clinical trial is to investigate the impact of performing cervical exercises during a simulated game on shoulder range of motion and strength in collegiate baseball picthers. The main questions it aims to answer are: Can performing cervical retraction/extension …
Sponsor: Sacred Heart University • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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New protein therapy hopes to repair brain damage in rare disease
Disease control Recruiting nowThis is a single-center, prospective, randomized, open-label, blinded outcome assessment (PROBE) study. At the end of the PROBE study, patients who have completed the study may opt to enter the open-label extension (OLE) study. The objective of the study is to evaluate the safety…
Early phase 1 • Sponsor: Beijing Tiantan Hospital • Aim: Disease control
Last updated Jun 26, 2026 12:56 UTC
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New pain block method could improve shoulder surgery recovery
Symptom relief CompletedThis study aims to compare the serratus posterior superior intercostal plane block and suprascapular nerve block and axillary nerve block for analgesia in shoulder arthroscopic surgery.
Sponsor: Tanta University • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Heart artery balloon study seeks Long-Term answers
Knowledge-focused Recruiting nowCoronary stents are the best treatment method ever accepted in the treatment of coronary artery stenoses. Due to some limitations and complications of stent use, the operators tried to find new solutions. Drug Coated Balloons (DCBs) have been accepted as a new method in the treat…
Sponsor: Kutahya Health Sciences University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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New pain combo may help knee replacement patients recover faster
Symptom relief CompletedTotal knee arthroplasty (TKA) is commonly associated with significant postoperative pain, which may impair early mobilization and functional recovery. Multimodal analgesia techniques are widely used to improve postoperative pain control while minimizing opioid consumption. Local …
Sponsor: Ankara University • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Army researchers hunt for heat stroke warning signs in soldiers
Knowledge-focused Recruiting nowExertional heat stroke (EHS) affects \~500 Military Personnel and over 100 Soldiers every year, and it is believed that these numbers are underreported. EHS is the most severe form of exertional heat illness (EHI) and can result in substantial, long-lasting organ damage, and even…
Sponsor: United States Army Research Institute of Environmental Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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PrEP Users' gut bacteria under the microscope: antibiotic resistance alert
Knowledge-focused Recruiting nowThe importance of the study lies mainly in expanding knowledge of the phenomenon of antibiotic resistance in subjects using PrEP, studying for the first time in this population the resistance phenotype in commensal Enterobacterales of the gastrointestinal tract. The data obtaine…
Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Pain-Free wart cream for kids shows promise in new study
Symptom relief Recruiting nowWarts caused by the human papillomavirus (HPV) are one of the most common skin conditions among children. The prevalence of warts in school-aged children ranges from 10 to 20 percent. Warts are more common among immunocompromised patients \[1, 2\]. Some studies also show that the…
Sponsor: Mazandaran University of Medical Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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Can remote rehab match In-Person therapy for back pain?
Symptom relief CompletedA single blinded clinical randomized trial. A single blinded trained investigator examined all patients and collect all data to eliminate inter- investigator error. Patients will be divided according to the treatment procedure into two groups equal in numbers to investigate a com…
Sponsor: Ahmed Adel Eid • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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Vibrating platform or exercise: which eases chronic neck pain better?
Symptom relief CompletedChronic neck pain is a prevalent issue among young adults, potentially impacting pain levels, range of motion, posture, balance, and daily functional activities. This study is designed to compare two distinct physical therapy interventions for young individuals diagnosed with chr…
Sponsor: Pamukkale University • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Olive extract may boost fat burning during workouts
Symptom relief Recruiting nowThere is current research interest in the use of fruit and plant-based food products containing high levels of natural antioxidants and their impact on exercise, which may be particularly beneficial for recreationally or low-active populations. One such product is an olive extrac…
Sponsor: Anglia Ruskin University • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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High school students lead the charge against cancer screening gaps
Knowledge-focused Recruiting nowThis study engages youth as health advocates to increase cancer screening in their community. The study will evaluate the effectiveness of a youth-led intervention on cancer screening awareness in adults who are overdue for cancer screening.
Sponsor: Rutgers, The State University of New Jersey • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Arm strength may predict heart failure outcomes in device patients
Knowledge-focused By invitation onlyThe aim of this study is to evaluate in detail the factors that determine upper extremity function, determine its effect on prognosis, hospital admission, hospitalization, and mortality, and examine the results according to the use of different implantable cardiac implantable ele…
Sponsor: Hacettepe University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Can ultrasound help heal broken foot bones faster?
Symptom relief OngoingThis study examines the effect of using the AccelStim bone growth stimulator on subjects undergoing treatment for fresh metatarsal fractures.
Sponsor: Orthofix Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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Can an iPad program help older cancer patients stay strong?
Symptom relief OngoingThe purpose of this study is to find out whether an 8-week digital health promotion program called COBRA is a safe and practical (feasible) option for older adults with cancer/OAC.
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC