New protein treatment hopes to repair brain damage in rare disease

NCT ID NCT06765733

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 35 times

Summary

This early-phase trial is testing a new drug called Aleeto, a nerve repair protein, in 20 people with Multiple System Atrophy (MSA), a rare and progressive brain disorder. The study aims to see if Aleeto is safe and tolerable, and whether it shows any signs of helping with symptoms. Participants will receive the drug via injection into the spine or vein.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MULTIPLE SYSTEM ATROPHY - PARKINSONIAN SUBTYPE (MSA-P) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Tiantan Hospital, Capital Medical University

    RECRUITING

    Beijing, Beijing Municipality, 100070, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Aleeto (a nerve repair protein derived from stem cells)

What this could lead to

If it works, this could point toward a treatment that slows or repairs nerve damage in Multiple System Atrophy, a rare and devastating disease.

What could go wrong

This is a very early, small trial (20 people) focused on safety, not proof of effectiveness. The treatment may not work or could have side effects.

Conditions

The condition(s) this trial relates to.

multiple system atrophy thyroid dyshormonogenesis 2A

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.