Cure My Disease

Don't miss your cure!

 Log in / Sign up

DNA hunt launched for rare brain diseases – no treatment yet

NCT ID NCT06647641

Recruiting now Knowledge-focused Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Jan 18, 2026 · Last updated Apr 28, 2026 · Updated 21 times

Summary

This study collects blood samples from up to 1,000 adults with progressive supranuclear palsy (PSP), corticobasal syndrome (CBS), multiple system atrophy (MSA), or related conditions, plus their family members. Researchers will sequence the DNA to find known and new genetic variants linked to these diseases. The goal is to better understand the genetic causes, not to test a treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CORTICOBASAL SYNDROME (CBS) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

CORTICOBASAL DEGENERATION CORTICOBASAL DEGENERATION CORTICOBASAL DEGENERATION (CBD) CORTICOBASAL DEGENERATION (CBD) CORTICOBASAL DEGENERATION SYNDROME CORTICOBASAL DEGENERATION SYNDROME CORTICOBASAL SYNDROME CORTICOBASAL SYNDROME (CBS) MSA MSA MSA - MULTIPLE SYSTEM ATROPHY MSA - MULTIPLE SYSTEM ATROPHY MSA-C MSA-C MULTIPLE SYSTEM ATROPHY MULTIPLE SYSTEM ATROPHY (MSA) WITH ORTHOSTATIC HYPOTENSION MULTIPLE SYSTEM ATROPHY - CEREBELLAR SUBTYPE (MSA-C) MULTIPLE SYSTEM ATROPHY - PARKINSONIAN SUBTYPE (MSA-P) MULTIPLE SYSTEM ATROPHY - PARKINSONIAN SUBTYPE (MSA-P) MULTIPLE SYSTEM ATROPHY, CEREBELLAR TYPE MULTIPLE SYSTEM ATROPHY, PARKINSONIAN TYPE MULTIPLE SYSTEM ATROPHY, PARKINSONIAN TYPE PROGRESSIVE SUPRANUCLEAR PALSY PROGRESSIVE SUPRANUCLEAR PALSY (PSP) PSP PSP - PROGRESSIVE SUPRANUCLEAR PALSY