PrEP Users' gut bacteria under the microscope: antibiotic resistance alert

NCT ID NCT07370948

Recruiting now Knowledge-focused Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is checking for antibiotic-resistant bacteria in the gut of 200 people who take PrEP (HIV prevention pills). Researchers will collect rectal swabs during routine STI testing and analyze the bacteria for resistance. The goal is to understand how common resistance is in this group and to help create programs that promote smarter antibiotic use.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could lead to better monitoring programs and guidelines for using antibiotics wisely in PrEP users, helping to slow antibiotic resistance.
What could go wrong: This is an observational study, not a treatment trial. It only measures resistance patterns and does not test any intervention, so direct health benefits are not expected.

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Conditions

The condition(s) this trial relates to.

Infections infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INFECTION

Contacts and locations

Locations

IRCCS Azienda Ospedaliero-Universitaria di Bologna
RECRUITING

Bologna, Bologna, 40138, Italy

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