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116076 trials found · Page 2974 of 5804
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Scientists hunt for genetic clues to severe viral infections
Knowledge-focused Recruiting nowBackground: * Infections caused by viruses are common causes of illnesses: the common cold, many ear infections, sore throats, chicken pox, and the flu are caused by different viruses. Usually, these illnesses last only few days or, at most, a few weeks. Some virus infections li…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Jul 10, 2026 00:00 UTC
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New combo pill shows promise for type 2 diabetes in japanese patients
Disease control CompletedThe purpose of this study is to evaluate the safety and efficacy of MP-513 (Teneligliptin) in combination with Sulfonylurea in patients with type 2 Diabetes for 12 weeks administration and to evaluate the safety and efficacy of MP-513 in combination with Sulfonylurea with an exte…
Phase: PHASE3 • Sponsor: Tanabe Pharma Corporation • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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New antibody drug shows promise for blocking asthma attacks
Disease control CompletedThis Phase II, double-blind, placebo-controlled, randomized, parallel-group study is designed to evaluate the efficacy, safety, and tolerability of huMAb OX40L administered to patients by IV infusion for the treatment of allergen-induced asthma.
Phase: PHASE2 • Sponsor: Genentech, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:39 UTC
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New diabetes drug shows promise in 12-Week trial
Disease control CompletedThe purpose of this study is to evaluate the efficacy and safety of MP-513 (Teneligliptin) in patients with type 2 Diabetes for 12 weeks administration.
Phase: PHASE3 • Sponsor: Tanabe Pharma Corporation • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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New diabetes combo drug shows promise in early trial
Disease control CompletedThe purpose of this study is to evaluate the safety and efficacy of MP-513 in combination with Metformin in patients with type 2 diabetes for 24 weeks administration and to evaluate the safety and efficacy of MP-513 in combination with Metformin with an extension treatment for up…
Phase: PHASE2 • Sponsor: Tanabe Pharma Corporation • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Botox injection shows promise for restless legs relief
Symptom relief CompletedRestless Legs Syndrome (RLS) is a common sensori-motor disorder that causes sensory discomfort and motor restlessness, most often in the legs, which improves with movement. Although medications are available to treat the disorder, many people either experience side effects that p…
Phase: PHASE2 • Sponsor: University Hospital, Bordeaux • Aim: Symptom relief
Last updated Jun 27, 2026 12:32 UTC
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New breathing technique could sharpen lung cancer scans
Diagnosis CompletedFluorodeoxyglucose (FDG) positron emission tomography (PET) is now widely used for cancer imaging purpose, notably for preoperative work-up. It aims at visualizing organs metabolism. In case of cancer, metabolism is, classically, increased and some hot spots are visible on PET im…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Diagnosis
Last updated Jun 26, 2026 19:11 UTC
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Pregnancy's hidden clues: could past pregnancies shape breast cancer outcomes?
Knowledge-focused Recruiting nowThis study plans to learn more about the immune system's response to breast cancer in young women.
Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Can waiting a few minutes after a heart attack save more heart muscle?
Disease control CompletedThe investigators previously reported that angioplasty postconditioning reduces infarct size (cardiac enzyme release) in STEMI patients with a fully occluded coronary artery at hospital admission. Animal studies have suggested that the time window for applying brief episodes of i…
Phase: PHASE2 • Sponsor: Hospices Civils de Lyon • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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New skin patch could replace flap surgery for leg injuries
Disease control CompletedComparison of 2 techniques of surgery on patients with inferior limb traumatic wounds: the innovative technique Integra® and the technique of reference: the flap surgery.
Phase: PHASE3 • Sponsor: University Hospital, Bordeaux • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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New sound test could spot thyroid cancer without needles
Diagnosis Recruiting nowThis study is being done to identify and differentiate thyroid nodules by acoustic imaging and viscoelastic parameters.
Sponsor: Mayo Clinic • Aim: Diagnosis
Last updated Jun 27, 2026 12:00 UTC
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Stem cell bone graft shows promise for back pain relief
Disease control CompletedThis study is being conducted to determine the percentage of patients with solid spinal fusions after being treated with Osteocel Plus in a TLIF procedure. Due to the unique processing conditions, Osteocel Plus retains a high concentration of stem cells in conjunction with the al…
Sponsor: NuVasive • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New ultrasound technique could spot dangerous placenta condition earlier
Diagnosis CompletedAbnormally invasive placenta (AIP) is defined as an abnormal placental attachment of a part or the entire chorionic plate with penetration of chorionic villi in the myometrium and absence of the decidua basalis. This anomaly is associated with significant maternal morbidity and m…
Phase: NA • Sponsor: University Hospital, Tours • Aim: Diagnosis
Last updated Jun 27, 2026 08:06 UTC
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Could HIV patients safely pause their meds? new study explores
Disease control CompletedThe primary objective of the trial is to assess the ability of an early and intermittent antiretroviral therapy in maintaining an immunological stability in antiretroviral naive HIV infected adults, to offer a potential alternative strategy to differed and continuous antiretrovir…
Phase: PHASE2 • Sponsor: ANRS, Emerging Infectious Diseases • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Spine steroid shot eases back pain for a month, but not a year
Symptom relief CompletedTo assess the efficacy on pain level at 1 month and 12 months of a steroid injection in the inter-vertebral disc for patients with chronic back pain and inflammatory discopathy on magnetic resonance imaging. Hypothesis: delivering anti-inflammatory drugs in situ may decrease bac…
Phase: PHASE4 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief
Last updated Jun 26, 2026 16:28 UTC
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New blood score could predict septic shock survival
Knowledge-focused CompletedA prognostic score was proposed by the investigative team to predict death at 1 month. This score is based on certain biological markers, scored under emergency conditions in the first 24 hours of routine clinical practice management for septic shock. The main objective of this …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Heart attack study tests simple procedure to limit damage
Knowledge-focused CompletedAfter having shown that postconditioning allowed a significant 36% reduction of infarct size as assessed by blood levels of myocardial enzymes in acute myocardial patients, the investigators objective is to assess the effect of postconditioning in acute myocardial infarction (AMI…
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Hunt for genes behind rare bone disease could unlock future treatments
Knowledge-focused Recruiting nowCMD can be inherited in an autosomal dominant or recessive trait. CMD may also be caused by de novo mutations. The goal of this study is to identify genes and regulatory elements on chromosomes that are the cause for CMD. The investigators also study blood samples and tissue samp…
Sponsor: UConn Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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Experimental drug cocktail targets Hard-to-Treat cancers
Disease control OngoingThis phase I trial is studying the side effects and best dose of erlotinib hydrochloride when given together with GDC-0449 with or without gemcitabine hydrochloride in treating patients with metastatic pancreatic cancer or solid tumors that cannot be removed by surgery. Drugs use…
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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Lamp vs laser: which light works best for vitiligo?
Disease control Completed308 nm excimer lamp and 308 nm excimer laser have both provide interesting results in treating vitiligo. They have the same wavelength but the type of emission of the photons is different. To date there is no direct comparative data concerning these two devices in this indication…
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC