New imaging reveals how cyclosporine eye drops calm dry eye inflammation

NCT ID NCT06898853

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will test whether 0.1% cyclosporine A eye drops can change the number and behavior of immune cells on the eye's surface in people with dry eye disease. Researchers will use a special microscope to watch these cells move over 12 weeks and compare the drops to a lubricating eye drop. The goal is to understand how cyclosporine A reduces inflammation, which could improve future treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

0.1% cyclosporine A eye drops

What this could lead to

If successful, this could help doctors understand exactly how cyclosporine A calms the immune response in dry eye, leading to better-targeted treatments.

What could go wrong

This is a small, early-stage study (60 people) that focuses on measuring immune cells, not on curing symptoms. The results may not apply to all dry eye patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

dry eye syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • School of Optometry and Vision Science

    RECRUITING

    Sydney, New South Wales, 2033, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••