Could the 'Love Hormone' ease surgery pain and cut opioid use?
NCT ID NCT06483659
First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 2 times
Summary
This study tests whether giving oxytocin (the 'love hormone') through an IV during surgery can reduce pain and the need for opioid painkillers after a minimally invasive hysterectomy. Researchers will compare oxytocin to a placebo in 152 adults aged 18-65. The goal is to find a safer way to manage post-operative pain.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Oxytocin (Pitocin)
- What this could lead to
- If it works, this could offer a new way to manage post-surgery pain and reduce reliance on opioids.
- What could go wrong
- This is an early phase 2 trial with only 152 participants, so results may not apply broadly. Oxytocin may not outperform placebo for pain relief.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Brigham and Women's Hospital
RECRUITINGBoston, Massachusetts, 02215, United States
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Other studies related to the condition(s) this trial covers.
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