University Of Virginia
Clinical trials sponsored by University Of Virginia, explained in plain language.
-
Appalachian study tests tech to cut sugary drink intake
Disease control CompletedThis study tested a program called iSIPsmarter, which uses text messages and online tools to help adults in rural Appalachia drink fewer sugary beverages like soda and sweet tea. About 249 adults who drank at least 200 calories of sugary drinks daily took part. The program was co…
Phase: NA • Sponsor: University of Virginia • Aim: Disease control
Last updated Apr 30, 2026 15:51 UTC
-
Can a seizure drug help you quit drinking and smoking?
Disease control CompletedThis study tested whether topiramate, a seizure medication, helps people who are dependent on both alcohol and nicotine quit both substances. 236 adults who drank heavily and smoked at least 5 cigarettes daily received either a high or low dose of topiramate or a placebo. The mai…
Phase: PHASE2, PHASE3 • Sponsor: University of Virginia • Aim: Disease control
Last updated Apr 30, 2026 15:51 UTC
-
New bleeding treatment for tiny hearts shows promise
Disease control CompletedThis study tested whether a purified clotting medicine (fibrinogen concentrate) works as well as a standard blood product (cryoprecipitate) to control bleeding in infants after heart surgery. Thirty-one children under 2 years old were randomly assigned to receive one of the two t…
Phase: PHASE4 • Sponsor: University of Virginia • Aim: Disease control
Last updated Apr 29, 2026 15:14 UTC
-
New CGM algorithm could simplify insulin dosing for diabetes patients
Disease control CompletedThis study tested whether a continuous glucose monitor (CGM) based algorithm helps people with type 2 diabetes adjust their long-acting insulin doses better than the usual finger-stick method. Thirty adults already using basal insulin were followed for 18 weeks. The goal was to s…
Phase: NA • Sponsor: University of Virginia • Aim: Disease control
Last updated Apr 29, 2026 15:01 UTC
-
No more carb counting? new insulin tool tested in small trial
Disease control CompletedThis study tested a new tool called InsuLearn that helps people with type 1 diabetes calculate their insulin doses without needing to count carbohydrates. Seven adults on multiple daily injections tried the tool for a day and compared it to their usual care. The goal was to see i…
Phase: NA • Sponsor: University of Virginia • Aim: Disease control
Last updated Apr 26, 2026 20:01 UTC
-
Diabetes tech gets personal: new system learns your habits to control blood sugar
Disease control CompletedThis study tested a computer system that gives personalized advice to people with type 1 diabetes based on their continuous glucose monitor readings. The goal was to see if tailoring advice to each person's behavior and mindset could improve blood sugar control better than standa…
Phase: NA • Sponsor: University of Virginia • Aim: Disease control
Last updated Apr 26, 2026 20:00 UTC
-
Your phone could soon diagnose balance disorders
Diagnosis CompletedThis study tested whether a smartphone app can accurately measure how well your eyes and balance system work together. 35 adults with and without balance problems performed a standard head-movement test using both a smartphone app and a professional computer system. The goal is t…
Sponsor: University of Virginia • Aim: Diagnosis
Last updated Apr 30, 2026 15:49 UTC
-
Phone app plus coaching eases emotional distress in breast cancer survivors
Symptom relief CompletedThis study tested whether a mobile app called IntelliCare could help reduce depression and anxiety in women who had breast cancer. 313 survivors who were diagnosed within the past 5 years and had high levels of distress used the app, with some also receiving extra coaching. The g…
Phase: NA • Sponsor: University of Virginia • Aim: Symptom relief
Last updated Apr 28, 2026 13:02 UTC
-
New camera technique reveals hidden tissue stiffness
Knowledge-focused CompletedThis study tested a new, non-invasive way to measure muscle stiffness by taking images of the skin on the back. Five adults, either healthy or with mild neck pain, had their skin gently pulled and stretched while cameras recorded the movement. The goal was to see if this imaging …
Phase: NA • Sponsor: University of Virginia • Aim: Knowledge-focused
Last updated May 01, 2026 16:01 UTC
-
Can a lifestyle program lower health risks for endometrial cancer survivors?
Knowledge-focused CompletedThis study tested a group-based program to help endometrial cancer survivors adopt healthier habits. The goal was to lower their risk of other health problems like heart disease and diabetes. Twenty-three survivors who had completed cancer treatment took part in online learning a…
Phase: NA • Sponsor: University of Virginia • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:52 UTC
-
Breath-Taking MRI reveals how air moves in diseased lungs
Knowledge-focused CompletedThis study used a special MRI with helium gas to measure how fast air moves in the windpipe of healthy people and those with lung diseases like COPD. The goal was to gather real measurements to improve computer models that predict airflow problems. 24 adults took part in this obs…
Phase: NA • Sponsor: University of Virginia • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:52 UTC
-
Exercise study reveals how workout intensity impacts hunger hormones
Knowledge-focused CompletedThis study looked at how different exercise intensities change levels of ghrelin, a hormone that controls hunger, in 40 adults with obesity and prediabetes. Researchers measured ghrelin, appetite, and blood vessel function after exercise. The goal was to understand how exercise a…
Phase: NA • Sponsor: University of Virginia • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:48 UTC
-
Computer models aim to predict sepsis in fragile newborns
Knowledge-focused CompletedThis pilot study tested whether computer models could predict sepsis and a serious gut infection called NEC in very low birth weight infants (under 1500 grams). Researchers used data from 144 babies in the NICU to build and test these models. The goal was to see if the approach w…
Sponsor: University of Virginia • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:01 UTC