Can a seizure drug curb both drinking and smoking?
NCT ID NCT01182766
First seen Nov 01, 2025 · Last updated Jun 12, 2026 · Updated 34 times
Summary
This study tested whether topiramate, a seizure medication, helps people who are dependent on both alcohol and nicotine. 236 adults took either a high or low dose of topiramate or a placebo for 18 weeks. The main goals were to see if the drug helped them stop smoking and reduce heavy drinking days.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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University of California, San Diego
La Jolla, California, 92093, United States
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University of Texas MD Anderson Cancer Center
Houston, Texas, 77030, United States
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University of Virginia Center for Addiction Research & Education
Charlottesville, Virginia, 22911, United States
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University of Virginia Center for Addiction Research & Education
Richmond, Virginia, 23294, United States
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.