Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Could a stomach problem harm your lungs? new study investigates

NCT ID NCT05716022

Knowledge-focused Sponsor: University of Virginia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study from the University of Virginia looked at whether having a hiatal hernia (a stomach issue) is linked to early, undetected lung scarring. Researchers collected blood and lung fluid samples from 14 adults before surgery to measure signs of lung injury. The goal was to see if stomach contents leaking into the lungs might trigger early fibrosis, which could lead to better ways to catch and prevent lung disease.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If the link is confirmed, it could point to hiatal hernia as a risk factor for lung fibrosis, enabling earlier detection and prevention.
What could go wrong
This is a very small, completed observational study with only 14 participants. It does not test any treatment, and results may not apply to broader populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

14 people

The number who actually took part.

Started

Jan 2023

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

1. Participants without a clinical diagnosis of pulmonary fibrosis will be recruited from UVA medical center based on the absence of traction bronchiectasis, honeycombing and/or reticular opacities on CT Scan. 2. Case group will be adults who have a clinical diagnosis of hiatal hernia already scheduled to under surgical repair 3. Control group will be adults without a CT diagnosis of hiatal hernia who have been scheduled to undergo Bronchoscopy for lung nodule evaluation.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Able to provide written consent. 2. Clinical diagnosis of hiatal hernia and/or gastroesophageal reflux undergoing pre-operative evaluation for surgical repair at the University of Virginia as part of clinical care. 3. 18 years and above. Exclusion Criteria: 1. Unable to provide written consent. 2. Clinical diagnosis of pulmonary fibrosis. 3. History of hiatal hernia (for control group only). 4. Use of home supplemental oxygen therapy either at rest or exertion. 5. Pregnant Women (will be confirmed as part of standard of care).

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Hiatal hernia are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

hiatus hernia interstitial lung disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hiatal hernia Interstitial lung disease

Contacts and locations

Locations

  • University of Virginia

    Charlottesville, Virginia, 22908, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.