Could a stomach problem harm your lungs? new study investigates

NCT ID NCT05716022

First seen Mar 17, 2026 · Last updated Jun 23, 2026 · Updated 18 times

Summary

This completed study from the University of Virginia looked at whether having a hiatal hernia (a stomach issue) is linked to early, undetected lung scarring. Researchers collected blood and lung fluid samples from 14 adults before surgery to measure signs of lung injury. The goal was to see if stomach contents leaking into the lungs might trigger early fibrosis, which could lead to better ways to catch and prevent lung disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Virginia

    Charlottesville, Virginia, 22908, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If the link is confirmed, it could point to hiatal hernia as a risk factor for lung fibrosis, enabling earlier detection and prevention.

What could go wrong

This is a very small, completed observational study with only 14 participants. It does not test any treatment, and results may not apply to broader populations.

Conditions

The condition(s) this trial relates to.

hiatus hernia interstitial lung disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.