Could a stomach problem harm your lungs? new study investigates

NCT ID NCT05716022

Completed Knowledge-focused Sponsor: University of Virginia Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study from the University of Virginia looked at whether having a hiatal hernia (a stomach issue) is linked to early, undetected lung scarring. Researchers collected blood and lung fluid samples from 14 adults before surgery to measure signs of lung injury. The goal was to see if stomach contents leaking into the lungs might trigger early fibrosis, which could lead to better ways to catch and prevent lung disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If the link is confirmed, it could point to hiatal hernia as a risk factor for lung fibrosis, enabling earlier detection and prevention.
What could go wrong: This is a very small, completed observational study with only 14 participants. It does not test any treatment, and results may not apply to broader populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hiatus hernia interstitial lung disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIATAL HERNIA INTERSTITIAL LUNG DISEASE

Contacts and locations

Locations

University of Virginia

Charlottesville, Virginia, 22908, United States

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