University Of Pennsylvania

This study looked at two common blood pressure medicines—calcium channel blockers and beta-blockers—in 50 adults with heart failure with preserved ejection fraction (HFpEF) and high blood pressure. The goal was to see which drug works better at lowering blood pressure and improvi…

This study tested whether sending text message reminders to patients and nudging their doctors could increase flu vaccination rates. Over 26,000 adults aged 50 and older took part. The approach used simple, low-cost tools like pre-visit texts and automatic vaccine orders in the e…

This study tested a program at Pennsylvania Hospital where visitors and patients who carry firearms could get free cable locks or lock boxes to store their guns safely. Researchers wanted to see if people would use these devices and how to best collect data on it. The goal is to …

This study tested a gentle brain stimulation technique (tDCS) combined with language therapy in 23 people with primary progressive aphasia, a condition that slowly destroys speech. Participants received either real or fake stimulation over 10 days, and researchers measured change…

This study tested whether a low dose of naltrexone, a drug normally used for alcohol dependence, can improve physical health and quality of life in people with vasculitis (a group of rare blood vessel diseases). Sixty adults with different types of vasculitis took either the low …

This study looked at whether a teamwork program called TeamSTEPPS, originally designed for hospitals, could be adapted for school mental health teams. Researchers worked with 90 participants including mental health providers, teachers, and school leaders to see if the program was…

This study looked at whether opioid use disorder and non-fatal overdoses cause a harmful protein called tau to build up in the brain. Researchers used special PET/CT scans on 12 adults, including those with opioid use disorder and healthy volunteers. The goal was to understand lo…

This study used MRI scans and blood tests to see how a single use of an e-cigarette (with or without nicotine) or a tobacco cigarette affects blood vessel function and inflammation. 55 current smokers and vapers were compared to a group of non-smokers/non-vapers. The goal was to …

This early-phase study looked at how nerves and hormones control blood sugar in 9 people with type 1 diabetes who had received islet cell transplants. Researchers used special drugs to block certain signals and measured hormone responses during low blood sugar. The goal was to le…

This study looked at whether a heart ultrasound (TEE) should be used routinely or only when needed during low-risk coronary bypass surgery. Researchers enrolled 40 adults with good heart function to test if such a study is feasible. The goal is to help doctors decide when TEE is …