University Of Pennsylvania

This study tests whether giving people leaving prison a monthly cash payment ($1,000 for the first month, then $750 for 11 months) helps them stay healthy, find stable housing, avoid going back to jail, and manage their finances. Researchers will follow 450 adults in Nebraska for…

This early-phase study tests a new approach for people with certain blood cancers (like lymphoma) that have returned or not responded to standard therapy. Participants receive their own immune cells that have been modified to attack cancer cells, along with specially edited stem …

This study tests whether adding a second thyroid hormone (T3) to the standard T4 treatment can improve persistent symptoms like fatigue and brain fog in people with hypothyroidism. It involves 60 adults aged 18-70 who still have symptoms despite normal thyroid blood tests. Partic…

This study tests whether duloxetine, a medication that affects brain signals, can reduce disability and psychological distress in adults with inflammatory bowel disease (IBD). About 32 participants will take duloxetine for a period, and researchers will measure changes in anxiety…

This study tests a botulinum toxin called DaxibotulinumtoxinA (DAXI) for adults with blepharospasm, a condition causing uncontrollable blinking or eye muscle spasms. Twenty participants will receive up to three injection cycles over 12 months. The goal is to measure how long symp…

This early-phase study looks at whether taking aspirin at specific times of day can prevent the blood pressure increases that often happen with the pain reliever celecoxib. Researchers will monitor blood pressure in 60 healthy adults over time. The goal is to learn how timing aff…

This study tests whether evolocumab, a drug that lowers 'bad' cholesterol, changes the cells in the wall of an abdominal aortic aneurysm. About 44 people scheduled for aneurysm repair will receive either the drug or a placebo before surgery. Researchers will then compare the tiss…