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Could a low-dose addiction drug ease vasculitis symptoms?

NCT ID NCT03482479

First seen Jan 23, 2026 · Last updated Apr 29, 2026 · Updated 15 times

Summary

This study tested whether a very low dose of naltrexone, a drug normally used for alcoholism, can improve physical health and quality of life in people with vasculitis (a group of rare blood vessel diseases). Sixty adults with different types of vasculitis took either the drug or a placebo. The goal was to see if the drug helps more than a placebo in reducing symptoms like pain and fatigue.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • St. Joseph's Healthcare

    Hamilton, Ontario, Canada

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, 15260, United States

  • University of Utah

    Salt Lake City, Utah, 84112, United States

Conditions

Explore the condition pages connected to this study.