University Of Nebraska

This study tested whether adding trastuzumab to standard chemotherapy before surgery helps shrink breast tumors more effectively. About 92 women with early-stage breast cancer (some HER2-positive, some HER2-negative) took part. The goal was to see if the combination reduces the a…

This study tests two treatments—oral isotretinoin (an acne medication) and hCG injections—to see if they can help men with low or no sperm count produce moving sperm. About 100 men aged 19 to 50 will receive one of the treatments for three months. The goal is to find new options …

This study tests whether adding the drug palbociclib to standard hormone therapy before surgery can shrink tumors in people with early-stage hormone receptor-positive, HER2-negative breast cancer. About 51 participants will receive the combination for several months before their …

This study tests a new drug called BMX-001 added to standard radiation and chemotherapy for people with newly diagnosed anal cancer. The goal is to see if BMX-001 can reduce severe side effects like rectal bleeding and skin damage while still fighting the cancer. About 24 adults …

This early-phase study looks at whether giving low-dose radiation before CAR T-cell therapy is practical and safe for people with B-cell lymphoma that has returned or not responded to treatment. About 33 adults will receive radiation to shrink tumors while waiting for their CAR T…

This study tests whether adding a short, high-dose radiation boost to the main lung tumor, along with the immunotherapy drug durvalumab, is safe and effective for people with stage III non-small cell lung cancer after standard chemoradiation. About 6 participants will receive thi…

This early-stage study tests whether a single dose of psilocybin, the active ingredient in magic mushrooms, can reduce depression and anxiety in people with advanced pancreatic, biliary, or other gastrointestinal cancers. 24 participants and their family members are involved. The…

This study looks at whether a virtual reality (VR) camp can improve how children with hemiplegic cerebral palsy use their affected hand and arm. Seventeen children will receive 40 hours of either VR-based or standard hand-arm training over two weeks. Researchers will measure chan…

This study follows about 163 adults who had knee or hip replacement surgery and were sent home with opioid pain pills. Researchers teach patients how to safely store and destroy unused pills, then check in 6-8 weeks later to see what they did with them. The goal is to learn how w…

This study aimed to understand how the sounds of your own footsteps help you walk steadily. Researchers planned to have healthy adults walk while listening to altered versions of their footstep sounds to see if it changed their balance. The study was withdrawn before any particip…

This study looks at how well a long-acting HIV treatment (given as shots every two months) works for people living far from big cities. About 55 patients and their clinic staff will answer surveys and interviews over 15 months. The goal is to understand what helps or hinders gett…

This study was designed to test the drug ONC201 in people with a type of brain tumor called meningioma that had come back or wasn't responding to other treatments. The plan was to measure how much drug gets into the tumor during surgery and how long it keeps the tumor from growin…

This study looks at why some people with chronic ankle instability recover poorly. Researchers will test 42 active adults to find differences in brain activity and movement control between subgroups. The goal is to create better, evidence-based rehab programs.

This study looks at whether continuous glucose monitors (CGMs) can help underserved adults with type 2 diabetes better manage their blood sugar. About 50 participants with high A1c levels will use a CGM for 6 months, and researchers will track changes in blood sugar control and a…

This study compares new, less invasive ways to collect samples for detecting respiratory viruses like COVID-19. Instead of the standard deep nose swab, researchers are testing a nasal wash, saliva drool, and a special saliva cup. About 1,000 emergency room patients will provide s…