Magic mushroom therapy tested for easing cancer Patients' mental anguish

This small, early-stage study is testing whether a guided therapy session using psilocybin (the active compound in 'magic mushrooms') can help reduce severe depression, anxiety, and emotional distress in people with advanced, incurable gastrointestinal cancers. The study involves 24 patients who will receive preparatory counseling, a single supervised psilocybin session, and follow-up support. Researchers will measure changes in psychological distress and also observe a family member of each participant to understand the broader impact.