University Of Calgary

This study tests whether specially designed viruses called bacteriophages can eliminate a persistent bacterial infection in a hip replacement. Only one person will take part, someone who has tried all standard treatments without success. The treatment involves injecting the phage…

This study looks at two methods of giving muscle relaxants to patients with severe lung failure (ARDS) in the ICU. One method gives the drug as needed in small doses, while the other gives it continuously through an IV. The goal is to find out which approach is safer and works be…

This study tests a program called Moxie that sends weekly health tips by mail and offers a mobile app to help people manage chronic conditions like heart disease, diabetes, and kidney disease. The goal is to see if it reduces the number of times people are readmitted to the hospi…

This study looks at whether a genetic test called Thyroid GuidePx® can help doctors and patients with papillary thyroid cancer make better treatment choices. About 85 adults with small thyroid tumors will take the test before surgery. Researchers will see if the test results chan…

This study tests whether a microwave imaging device can detect breast implants in women. Ten women with implants placed at least 6 months ago will be scanned. The goal is to see if the scanner can find the implants and compare images of both breasts.

This study tests a new approach to prevent ventilator-associated pneumonia (VAP), a common and serious lung infection in ICU patients on breathing machines. Researchers will use a rapid test (about 4 hours) to identify harmful bacteria in the airway, then give a targeted inhaled …

This small pilot study tests whether a special gel called CO2Lift can reduce wound breakdown after breast reduction surgery. Ten women will have the gel applied to one breast and a placebo to the other right after surgery and daily for 6 days. Researchers will check if it's possi…

This study tests if a gentle electrical stimulation on the ear (called auricular vagal neuromodulation) can help people with Postural Orthostatic Tachycardia Syndrome (POTS). POTS causes a rapid heart rate upon standing, along with other symptoms like brain fog and fatigue. The s…

This study tests whether psilocybin (the active ingredient in magic mushrooms) combined with Acceptance and Commitment Therapy can reduce PTSD symptoms in adults who have survived intimate partner violence. 76 participants will receive either a high dose (25 mg) or a low dose (1 …

This early-stage study tests whether a non-invasive brain stimulation technique called rTMS is safe and can help ease depression and fatigue in adults with multiple sclerosis (MS). About 20 participants with MS and moderate-to-severe depression will receive daily rTMS sessions fo…

This study looks at whether a 12-week program of pelvic floor exercises, extra health information, and mental health support before prostate surgery can help men recover more quickly. About 40 men with an enlarged prostate will be split into two groups: one gets standard care, th…

This study tests a pain relief method called cryoneurolysis, which uses cold to temporarily stop nerves from sending pain signals. It is for 30 adults waiting for hip or knee replacement who currently take daily opioids. The goal is to see if this approach can lower pain and redu…

This study tests a new, drug-free treatment for vestibular migraine, a condition causing repeated dizziness and headaches. Fifty adults will receive either real or placebo electrical stimulation behind the ears over two weeks. The goal is to see if the treatment is safe, comforta…

This observational study looks at how natural changes in estrogen and progesterone might affect depression in adolescent girls. About 94 teens assigned female at birth with a history of depression will track their hormone levels daily at home and answer online surveys about their…

This study looks at when to start physical therapy after a stroke caused by a blocked artery. The goal is to see if waiting until day 3 is safer and helps recovery better than starting earlier. About 50 adults with persistent artery blockages will take part. The findings may guid…

This study aims to improve the quality of ECG (heart rhythm) recordings taken during cardiac MRI scans. The MRI's magnetic field can distort these signals, making it harder to monitor the heart. Researchers will test ways to reduce this distortion in 2,500 adult patients to impro…

This study looks at how different doses of oral THC (the active ingredient in cannabis) affect mood, heart rate, and drug feelings in healthy adults aged 18-55 who have used cannabis before without problems. Participants will attend four visits, each time receiving either a low, …