University Of Calgary

This study tests a step-by-step care plan for patients with severe breathing failure (ARDS) who need a breathing machine. The plan uses proven treatments like protective ventilation, paralysis, and prone positioning. Researchers will see if following this plan helps patients surv…

This study tests whether a transition coordinator can help 324 youth (ages 17-18) with type 1 diabetes successfully move from pediatric to adult diabetes care. Participants get extra support before, during, and after the switch. Researchers compare them to a group that didn't hav…

This study tests whether sending a letter (a 'nudge') from a pharmacist can encourage more adults to get their flu or travel vaccines. About 20,000 people in Alberta, Canada, are taking part. The researchers also want to see if getting vaccinated leads to fewer strokes in the fol…

This study tests a stepped care approach for 60 young people at high risk for psychosis. Participants start with the least intensive support (individual or group) and move to more focused therapy if needed. Researchers track symptoms and daily functioning over 18 months to see if…

This study tests whether adding online weight loss classes to standard cardiac rehab helps people with atrial fibrillation (AFib) and obesity lose at least 10% of their body weight and feel better. About 120 adults with AFib and a BMI of 30 or higher will take part. The goal is t…

This study tests whether adding a gentle, non-invasive brain stimulation technique (TMS) to a three-week intensive rehab program can help teens with severe chronic pain feel better. About 25 youth aged 10-18 will receive daily TMS sessions targeting a brain area linked to pain. R…

This study tests a procedure called genicular radiofrequency ablation (GRFA) for people who still have knee pain more than a year after knee replacement surgery. The treatment uses heat to calm the nerves around the knee. 44 participants will be randomly assigned to receive eithe…

This study aimed to see if a sphenopalatine ganglion (SPG) block—a numbing shot inside the nose—could quickly reduce anxiety in adults at electronic dance music festivals. Participants would have received either lidocaine or a saltwater placebo. The study was withdrawn before enr…

This study looks at how two parts of cannabis, THC and CBD, affect thinking and bladder problems in people with Multiple Sclerosis (MS). Thirty adults with MS will take either THC or CBD oil for 15 weeks and complete thinking tests and bladder symptom questionnaires. The goal is …

This study looks at a day camp for children with mild to moderate arm weakness (hemiparesis) from cerebral palsy or brain injury. Kids attend a two-week camp with special exercises to improve arm use. The main goal is to measure the cost of running the camp. About 40 children wil…

This study tests a new device called Gastric Alimetry that maps the stomach's electrical activity using a sticker-like patch. Researchers will compare readings from 200 healthy adults and people with stomach motility problems to establish normal ranges and see how signals relate …

This study looks at whether a volume-based feeding approach helps critically ill children in the pediatric ICU get the nutrition they need. Tube feedings are often interrupted, so kids may not get enough calories and protein. The trial will compare volume-based feeding (adjusting…

This study looks at whether using a child's genetic information can help doctors choose the right psychiatric medication with fewer side effects. About 6,000 children and young adults aged 6 to 24 who are starting or changing mental health medications will provide a saliva sample…

This study is testing a new microwave scanner that measures the electrical properties of breast tissue. Researchers want to see if these scans can be compared to mammograms in women who need follow-up breast imaging. About 20 women will be scanned with the microwave device on the…