University Hospital, Basel, Switzerland
Clinical trials sponsored by University Hospital, Basel, Switzerland, explained in plain language.
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Heart valve drug aims to stop stroke and kidney failure in one shot
Prevention CompletedThis study tested a drug called conestat alfa to see if it could prevent strokes and kidney injuries in people undergoing a minimally invasive heart valve replacement (TAVI). 141 patients with severe aortic stenosis received either the drug or a placebo before their procedure. Th…
Phase: PHASE2 • Sponsor: University Hospital, Basel, Switzerland • Aim: Prevention
Last updated Apr 30, 2026 15:51 UTC
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Psychedelic DMT tested as painkiller in healthy people
Symptom relief CompletedThis study looked at whether DMT, a psychedelic similar to LSD, can reduce pain in 17 healthy adults. Researchers used mild electrical shocks to cause pain and measured how DMT compared to ketamine and a placebo. The goal was to see if DMT could be a new option for treating pain …
Phase: PHASE1 • Sponsor: University Hospital, Basel, Switzerland • Aim: Symptom relief
Last updated May 01, 2026 16:01 UTC
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Weight-Loss drugs may boost your sex drive
Symptom relief CompletedThis study tested whether GLP-1 medications (like Ozempic) can improve sexual desire in overweight or obese men and women. 85 participants either took the drug plus made lifestyle changes, or only made lifestyle changes. The researchers measured changes in sexual thoughts, activi…
Sponsor: University Hospital, Basel, Switzerland • Aim: Symptom relief
Last updated May 01, 2026 15:58 UTC
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Cleft Surgery's hidden impact on palate blood flow revealed
Knowledge-focused CompletedThis study looked at how routine cleft repair surgery changes blood flow in the roof of the mouth. Researchers used a non-invasive probe to measure tissue oxygen levels before and after surgery in 77 patients. The goal was to understand the surgery's effect on healing and complic…
Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated May 01, 2026 16:01 UTC
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Heart labs go green: study reveals hidden waste costs
Knowledge-focused CompletedThis study looked at how much waste is produced during common heart procedures like angiograms and valve repairs. Researchers weighed and sorted trash from 40 procedures into paper, regular trash, medical waste, and recyclable plastic. They compared two waste-handling methods to …
Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated May 01, 2026 16:01 UTC
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Daylight and a hike may reset your internal clock better than office lighting
Knowledge-focused CompletedThis study looked at how different types of daylight and physical activity affect the body's internal clock and sleep. 51 healthy adults aged 18-35 took part. They were exposed to office lighting, natural daylight, or daylight with blue-light filtering glasses, and either rested …
Phase: NA • Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated May 01, 2026 16:00 UTC
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800 ICU patients studied to see if longer brain monitoring improves care
Knowledge-focused CompletedThis study looked at 800 adult ICU patients with brain problems to see if the length of EEG monitoring (a test that records brain activity) affects how doctors diagnose and treat them. Researchers reviewed past medical records from a single hospital to gather information on patie…
Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated May 01, 2026 15:59 UTC
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Scientists investigate how a key immune signal alters hormone effects on protein building blocks
Knowledge-focused CompletedThis study looked at how interleukin-6 (IL-6), an immune system signal, changes the way glucagon (a hormone) controls amino acid levels in the blood. 26 healthy volunteers received either a placebo or a drug that blocks IL-6, then had their amino acid and hormone levels measured.…
Phase: NA • Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated May 01, 2026 15:58 UTC
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Diabetes Drug's surprising effect on stress hormones revealed
Knowledge-focused CompletedThis study looked at how a single dose of semaglutide (Rybelsus), a drug used for diabetes, affects stress hormones like cortisol in healthy men. Twenty-two healthy male volunteers took either the drug or a placebo, and their cortisol levels were measured. The goal was to underst…
Phase: NA • Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated May 01, 2026 15:57 UTC
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Can wrist sensors get hospital patients moving?
Knowledge-focused CompletedThis study looked at whether activity sensors can be used in hospitals to track how much patients move. Nineteen hospitalized adults wore the sensors while staff measured the extra time and effort needed. The goal was to see if this technology could help reduce physical inactivit…
Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated May 01, 2026 15:56 UTC
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10,000 patients studied to speed up heart attack diagnosis
Knowledge-focused CompletedThis study looked at 10,000 people who came to the emergency room with chest pain. The goal was to see if new blood tests could help doctors find out faster if someone is having a heart attack. Researchers compared these new tests to the standard test to see which worked best.
Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:15 UTC
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Scientists test if common drugs can stop an LSD trip
Knowledge-focused CompletedThis study looked at whether giving ketanserin, olanzapine, or lorazepam after taking LSD can make the LSD effects weaker or end sooner. Twenty healthy adults took LSD alone or with one of these drugs, and researchers measured their experiences. The goal is to learn how to manage…
Phase: PHASE1 • Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:04 UTC
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AI could revolutionize online mental health care
Knowledge-focused CompletedThis study used artificial intelligence to predict how engaged people would be in online therapy and how much their symptoms would improve. Researchers analyzed data from over 6,600 people who took part in a digital therapy program. The goal was to create fair and accurate AI too…
Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:00 UTC