University Hospital, Basel, Switzerland
Clinical trials sponsored by University Hospital, Basel, Switzerland, explained in plain language.
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Bolus feeding may help ICU patients keep muscle
Disease control CompletedThis study tested whether giving protein in short bursts (intermittent feeding) is better than continuous feeding for preventing muscle wasting in critically ill patients. 113 adults in the ICU took part. The researchers measured how quickly patients reached their daily protein g…
Phase: NA • Sponsor: University Hospital, Basel, Switzerland • Aim: Disease control
Last updated Jun 22, 2026 12:08 UTC
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Sugar alcohol infusion may help diagnose thirst disorders
Diagnosis CompletedThis study tested whether infusing mannitol, a sugar alcohol, can help diagnose polyuria-polydipsia syndrome—a condition of excessive thirst and urination. Researchers measured copeptin levels in 42 healthy adults and patients after mannitol or placebo infusion. The goal was to s…
Phase: NA • Sponsor: University Hospital, Basel, Switzerland • Aim: Diagnosis
Last updated Jun 23, 2026 11:57 UTC
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New blood tests could speed up heart attack diagnosis in ER
Diagnosis CompletedThis study looked at 10,000 people who came to the emergency room with chest pain. The goal was to see if new blood tests could help doctors find heart attacks faster than current methods. Researchers compared these new markers with the standard test to see which worked best for …
Sponsor: University Hospital, Basel, Switzerland • Aim: Diagnosis
Last updated Jun 16, 2026 12:52 UTC
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New scanner could slash stroke diagnosis time
Diagnosis CompletedThis study tested whether a special CT scan done in the procedure room can accurately detect bleeding in the brain of stroke patients. The goal is to speed up diagnosis and treatment by avoiding extra trips to the regular CT scanner. 252 adults with stroke symptoms were enrolled …
Phase: NA • Sponsor: University Hospital, Basel, Switzerland • Aim: Diagnosis
Last updated Jun 15, 2026 19:06 UTC
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Heart valve drug shows promise in preventing brain and kidney damage
Prevention CompletedThis study tested a drug called conestat alfa in 141 people undergoing a minimally invasive heart valve replacement (TAVI) for severe aortic stenosis. The goal was to see if the drug could reduce the risk of small strokes and kidney damage that can happen after the procedure. Par…
Phase: PHASE2 • Sponsor: University Hospital, Basel, Switzerland • Aim: Prevention
Last updated Jun 10, 2026 13:26 UTC
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Weight-Loss drugs may boost your sex drive, study hints
Symptom relief CompletedThis study looked at whether GLP-1 analogues (like Ozempic or Wegovy) combined with lifestyle changes can improve sexual desire in overweight or obese men and women. 85 participants were followed to measure changes in sexual thoughts, activity, and overall sexual health. The goal…
Sponsor: University Hospital, Basel, Switzerland • Aim: Symptom relief
Last updated Jun 22, 2026 11:57 UTC
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Paws and play: can animal training boost resilience in kids?
Symptom relief CompletedThis study tested a 12-session outdoor group training program where children interacted with animals to build resilience. It included 107 children aged 2-4 or 8-12 who had either autism or a history of stressful life events. The goal was to see if this approach could help them be…
Phase: NA • Sponsor: University Hospital, Basel, Switzerland • Aim: Symptom relief
Last updated Jun 12, 2026 12:05 UTC
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App-Assisted physiotherapy shows promise for back pain relief
Symptom relief CompletedThis study tested whether using a smartphone app alongside standard physiotherapy helps people with low back pain more than physiotherapy alone. Sixty adults with low back pain lasting at least six weeks took part. Researchers measured changes in disability and pain levels to see…
Phase: NA • Sponsor: University Hospital, Basel, Switzerland • Aim: Symptom relief
Last updated Jun 10, 2026 13:29 UTC
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Which breast implant survives radiation best? study seeks answers
Knowledge-focused CompletedThis study looked at 1,000 women who had breast reconstruction with implants right after mastectomy, followed by radiation therapy. Researchers compared two types of implants—polyurethane-covered and non-polyurethane-covered—to see which had fewer complications like capsular cont…
Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Jun 23, 2026 20:33 UTC
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EEG timing could be key for ICU brain care
Knowledge-focused CompletedThis completed study from a Swiss hospital reviewed records of 800 adult ICU patients with brain problems to see how the length of EEG monitoring influenced their diagnosis and treatment. Researchers collected data on patient history, severity of illness, lab results, and outcome…
Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Jun 23, 2026 12:09 UTC
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Heart labs go green: study weighs procedure waste
Knowledge-focused CompletedThis study measured the amount and type of waste produced during heart procedures like angiograms and valve repairs. Researchers weighed and sorted waste into categories such as paper, regular trash, medical waste, and recyclable plastic. They compared two waste-handling methods …
Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Jun 23, 2026 11:59 UTC
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Scientists probe IL-6's role in amino acid control
Knowledge-focused CompletedThis completed study in 26 healthy volunteers tested whether blocking interleukin-6 (IL-6) changes how glucagon lowers amino acid levels in the blood. Participants received either a placebo or tocilizumab, a drug that blocks IL-6, followed by hormone infusions to mimic fasting an…
Phase: NA • Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Jun 23, 2026 11:56 UTC
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Brown fat: the hidden nutrient buffer?
Knowledge-focused CompletedThis study looked at whether brown fat helps the body handle nutrients from food better. Researchers compared 30 volunteers with and without active brown fat after they ate separate meals of protein, fat, and carbs. The goal was to see how brown fat affects energy use and blood s…
Phase: NA • Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Jun 22, 2026 12:08 UTC
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Swiss study probes ICU Workers' views on brain death and donation
Knowledge-focused CompletedThis completed study surveyed 338 nurses and doctors in Swiss intensive care units to understand their personal views, beliefs, and knowledge about brain death and organ donation. The goal was to identify how individual experiences and professional roles shape these perceptions. …
Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Jun 22, 2026 12:00 UTC
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Diabetes drug semaglutide may influence cortisol levels, small study suggests
Knowledge-focused CompletedThis completed study looked at how a single dose of semaglutide (Rybelsus), a drug used for diabetes and weight loss, affects cortisol and other stress hormones in healthy men. Twenty-two volunteers received either semaglutide or a placebo pill, and researchers measured changes i…
Phase: NA • Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Jun 22, 2026 11:59 UTC
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Scientists test if common drugs can stop an LSD trip
Knowledge-focused CompletedThis study looked at whether giving ketanserin, olanzapine, or lorazepam after taking LSD can make the psychedelic effects shorter or weaker. Twenty healthy adults took LSD and then one of these drugs or a placebo. The goal was to see how the drugs changed the intensity and durat…
Phase: PHASE1 • Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Jun 22, 2026 11:57 UTC
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AI could revolutionize online therapy by predicting who benefits most
Knowledge-focused CompletedThis study used artificial intelligence to predict how engaged people would be in online therapy and how much their symptoms would improve. Researchers analyzed data from over 6,600 adults who took part in a digital psychotherapy program. The goal was to create fair and accurate …
Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Jun 18, 2026 11:48 UTC
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Aging and thirst: new study reveals how water regulation changes with age
Knowledge-focused CompletedThis study looked at how healthy aging changes the body's ability to manage water levels. Researchers compared 32 older adults (60+) with younger adults (18-30) by measuring a hormone called copeptin during tests that raise and lower salt levels. The goal was to understand why ol…
Phase: NA • Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Jun 18, 2026 11:48 UTC
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Doctors put to the test: do they follow guidelines for coma care?
Knowledge-focused CompletedThis study watched 50 doctors from different specialties as they managed a pretend unconscious patient. The goal was to see if their decisions matched current medical guidelines. Results will help improve training and recommendations for coma care.
Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Jun 18, 2026 11:47 UTC
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MDMA's mirror images: which one works better?
Knowledge-focused CompletedThis study looked at how two different forms of MDMA (R-MDMA and S-MDMA) affect healthy people. 26 volunteers took part to measure feelings like mood and empathy, as well as physical changes like blood pressure and heart rate. The goal was to understand which form might be better…
Phase: PHASE1 • Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Jun 17, 2026 12:08 UTC
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Sunlight and a hike may reset your internal clock better than office lighting
Knowledge-focused CompletedThis study looked at how daylight and physical activity influence the body's internal clock and sleep. Fifty-one healthy adults aged 18-35 were exposed to different lighting conditions (office light, natural daylight, or daylight with blue-light-blocking glasses) and either reste…
Phase: NA • Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:49 UTC
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Can wrist sensors get hospital patients moving?
Knowledge-focused CompletedThis study looked at whether activity sensors can be easily used in hospitals to track how much patients move. 19 hospitalized adults who could walk but were on bed rest wore the sensors. Researchers measured how much extra time staff needed to use the sensors and how comfortable…
Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:48 UTC
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Cleft Surgery's hidden impact on palate blood flow revealed
Knowledge-focused CompletedThis study looked at how routine cleft repair surgery changes blood flow in the roof of the mouth. Researchers used a non-invasive probe to measure oxygen levels in the tissue before and after surgery in 77 patients. The goal was to understand the surgery's effect on tissue healt…
Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:07 UTC
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AI therapists in training: can computers teach better counseling?
Knowledge-focused CompletedThis study tested whether artificial intelligence (AI) can realistically simulate conversations between a therapist and a person with a mental health problem. Researchers used 520 simulated sessions to see if the AI could follow proper therapy techniques. The goal is to use these…
Phase: NA • Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Jun 11, 2026 11:57 UTC
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Psychedelic DMT tested for pain relief in healthy volunteers
Knowledge-focused CompletedThis study looked at whether DMT, a psychedelic drug, can reduce pain in healthy adults. Seventeen participants received DMT, ketamine, or a placebo, and their pain responses to mild electrical shocks were measured. The goal was to see if DMT has pain-relieving effects, which cou…
Phase: PHASE1 • Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Jun 09, 2026 12:08 UTC
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LSD study reveals how tiny doses alter perception and choices
Knowledge-focused CompletedThis study looked at how low doses of LSD change the way healthy adults make decisions based on what they see. Thirty participants completed computer tasks that tested their ability to predict and respond to visual patterns. The goal was to understand how LSD influences brain sig…
Phase: NA • Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Jun 05, 2026 12:06 UTC