Brown fat study reveals how your body handles carbs, fat, and protein
NCT ID NCT06078345
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at how brown adipose tissue (brown fat) helps the body process nutrients from food. Thirty healthy adults with or without active brown fat were given separate test meals of carbs, fat, or protein. Researchers measured blood sugar, fats, and energy use to see if brown fat acts as a nutrient buffer.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If it works, this could point toward ways to boost brown fat activity to improve metabolic health.
- What could go wrong
- This is a small, completed observational study, not a treatment trial. Results may not apply to people with metabolic diseases.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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30 people
The number who actually took part.
- Started
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Oct 2023
- Finished
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Aug 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 40 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * BMI 18.5 to 28 kg/m2 * Able to give informed consent as documented by signature Exclusion Criteria: * Concomitant medication other than prescription free analgesics (paracetamol and NSAID) and oral contraceptives * Other clinically significant concomitant disease states (e.g., renal failure, hepatic dysfunction, cardiovascular disease, diabetes mellitus) * Hyper- or hypothyroidism * Smoker / habitual tobacco use * Weight change of \>5% within 3 months prior to inclusion * Hypersensitivity to cold (e.g. Raynaud syndrome) * Known or suspected non-compliance, drug or alcohol abuse * Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. of the participant * Enrolment of the investigator, his/her family members, employees and other dependent persons * Enrolment into another study using ionizing radiation within the previous 12 months * Enrolment into another study including a pharmacological or nutritional intervention * Pregnancy or lactation * Lab parameters * Serum-Creatinine: above 1.5x upper limit of normal (ULN) * Glycated Hemoglobin (HbA1c): above 6.0% * Random plasma glucose \>11 mM
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University Hospital Basel, Dept. of Endocrinology
Basel, Switzerland
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