Can AI help surgeons pick the right gut length in Weight-Loss surgery?
NCT ID NCT07818317
First seen Sep 14, 2026 · Last updated Sep 15, 2026 · Updated 1 time
Summary
Researchers are studying whether three body measurements can help predict how well patients do after one-anastomosis gastric bypass. The measurements are the percentage of a laparoscopic instrument segment covered by fat, the total length of the small bowel, and a calculated abdominal index. Adults scheduled for this weight-loss surgery at participating centers take part. The study tracks weight loss at 12 and 24 months, nutritional outcomes, reflux, and complications, and it tests an explainable AI model that supports but does not replace the surgeon's decision.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- one-anastomosis gastric bypass surgery with an AI decision-support model
- What this could lead to
- If the model works, it could give surgeons a clearer way to pick limb length during gastric bypass, which may improve weight loss and lower the chance of nutritional problems.
- What could go wrong
- This is an observational study, not a randomized test, so it cannot prove that the AI model causes better outcomes. The model may not predict well in other hospitals, and measuring the small bowel and fat coverage adds time and variability to surgery.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2027
An estimate. Start dates often move.
- Expected to finish
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Nov 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The proposed registration is based on the current protocol design: a prospective observational cohort for model development and external validation, nested in routine one-anastomosis gastric bypass (OAGB) care. The current protocol does not prospectively assign a biliopancreatic-limb length, does not report patient-level results, and does not claim that any BPL length is optimal. The investigators not intend to assign participants prospectively to 0.5-, 1-, 2-, or 3-m BPL groups
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Adults aged 18 years or older at the time of consent. 2. Patients who meet the institution's independent clinical criteria for primary one-anastomosis gastric bypass. 3. Planned laparoscopic or robot-assisted OAGB at a participating centre. 4. Ability to undergo standardized intraoperative measurement of the J-I segment, P\_JI components, and total small-bowel length when clinically and ethically appropriate. 5. Ability to provide informed consent according to local requirements. 6. Willingness and reasonable ability to complete the prespecified postoperative follow-up. Exclusion Criteria: 1. Revisional, conversion, or non-primary gastric bypass surgery. 2. Operative anatomy that prevents reliable identification or measurement of the ligament of Treitz, the J-I segment, or the ileocecal junction. 3. Unaddressed altered gastrointestinal anatomy that is outside the development protocol. 4. Severe pre-existing malnutrition or another condition for which experimental variation in BPL length would be considered clinically inappropriate by the treating team. 5. Inability to provide informed consent when consent is required. 6. Inability to complete the minimum follow-up required by the approved protocol, unless the participant is retained for an approved missing-data or safety analysis. 7. Any intraoperative or postoperative circumstance in which the treating surgeon determines that protocol measurement would create unacceptable risk.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Oral Ospanov
Astana, Aqmola, 010000, Kazakhstan
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