University Hospital, Basel, Switzerland

This pilot study tests a simple method to reduce wound complications after groin vascular surgery. Surgeons will inject a blue dye into the skin around the surgical wound to make any lymphatic leaks visible, then repair them immediately. The study will enroll 60 adults and track …

This early-stage trial tests a new type of CAR T cell therapy that targets two proteins (CD19 and CD20) on cancer cells. It is for adults with B cell leukemia or lymphoma who have run out of standard options, including commercial CAR T cells. The main goal is to check the safety …

This study tests an IDO-1 inhibitor drug to see if it can safely prevent Epstein-Barr virus (EBV) infection in kidney transplant patients who have never had EBV but receive a kidney from a donor who has. Nine participants will take either the drug or a placebo for 28 days, and re…

This study tests whether giving a low dose of lorazepam (a sedative) early on can prevent delirium—a state of severe confusion—in intensive care patients who are at higher risk due to heavy alcohol use. Researchers will use a blood test called the Anttila-Index to identify these …

This study tests a new program where trained village health workers use tablet-based tools to provide HIV prevention services, including PrEP and emergency PEP, to people at high risk in rural Lesotho. About 380 participants will be enrolled to see if this approach increases mont…

This small study with 12 adults checks if wearable temperature sensors and an ingestible capsule can work together to track body temperature continuously for about 48 hours. The goal is to see if the data is complete, time-aligned, and easy to collect in everyday life. There is n…

This study gives 40 adults—half with autism, half without—a single dose of MDMA (the active ingredient in ecstasy) or a placebo to see how it changes oxytocin levels in the blood. Oxytocin is often called the 'love hormone' and helps with social bonding. The goal is not to treat …

This study tests whether sensory stimulation—like tasting and smelling food—affects how much energy your body uses to digest a meal. Twenty-four healthy volunteers will eat the same meal in two ways: normally by mouth, and through a tube that bypasses the senses. Researchers will…

This study compares a quick 3-step hand hygiene technique to the standard 6-step method recommended by the World Health Organization. Researchers want to see if the simpler method leads to better compliance among healthcare workers and still keeps hands clean. The trial will invo…

This study surveys 200 ICU doctors in Switzerland to understand how they use ultrasound to manage fluids and check for vein congestion. The goal is to learn what doctors know and how often they use these techniques. No treatments or procedures are tested—just a questionnaire.