SENSATION trial: can smelling and tasting your meal boost calorie burn?
NCT ID NCT07409025
First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 2 times
Summary
This study tests whether sensory stimulation—like tasting and smelling food—affects how much energy your body uses to digest a meal. Twenty-four healthy volunteers will eat the same meal in two ways: normally by mouth, and through a tube that bypasses the senses. Researchers will measure energy expenditure and skin temperature to see if sensory cues boost calorie burn.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help us understand how sensory cues like taste and smell influence how many calories we burn after a meal.
- What could go wrong
- This is a small, early-stage study in healthy people, so results may not apply to the general population or lead to any direct treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 24 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2026
- Expected to finish
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Jan 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 40 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * healthy volunteers of any gender * BMI between 18-25 kg/m2 * age between 18 and 40 years Exclusion Criteria: * concomitant medication except for prescription free analgetics (paracetamol, NSAIDs) and oral contraceptives * clinically significant concomitant disease states (e.g. renal failure, hepatic dysfunction, cardiovascular disease, diabetes mellitus), * allergy to local anaesthetic or any of the study meal ingredients * known or suspected non-compliance, drug or alcohol abuse * smoker / habitual tobacco use * habitual excessive alcohol consumption * inability to follow the procedures of the study * participation in another study with investigational drug within the 30 days preceding and during the present study * previous enrolment into the current study * enrolment of the investigator, his/her family members, employees and other dependent persons * uncontrolled hypo- or hyperthyroidism * pregnancy or lactation
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University Hospital Basel, Department of Endocrinology
RECRUITINGBasel, 4031, Switzerland
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