University Hospital, Angers

This study looks back at 10 years of medical records to compare different surgical techniques used to cure pilonidal sinus disease in children. It aims to find which surgery works best to heal the wound completely and prevent the painful condition from coming back. The results wi…

This study compares different surgical techniques for treating Hirschsprung disease, a rare condition where children are born without nerve cells in part of their bowel. Researchers will look at three surgical approaches to see which one helps children recover better and have few…

This study is testing whether a month of special visual computer exercises can improve mental speed and thinking skills in older adults with mild cognitive impairment. Researchers will compare the exercises to watching regular TV programs to see which helps more. The goal is to f…

This study is testing whether a high daily dose of nicotinamide (Vitamin B3) can help preserve or improve vision in people with Leber's hereditary optic neuropathy (LHON), a rare genetic disease that causes sudden, severe vision loss. It will enroll 13 people who developed LHON s…

This study aims to find out if changing the tubing connected to a patient's central IV line every 7 days is just as safe for preventing infections as changing it every 4 days. It will involve about 2,830 adult patients in intensive care units who need a central line. The goal is …

This study aims to see if doctors are missing dangerous blood clots in the lungs of patients hospitalized for sudden heart failure. It will compare two approaches across multiple hospitals: usual care versus systematically testing all eligible patients for these clots. The goal i…

This study is testing a simple 10-question checklist designed for video doctor visits to help figure out if a child's stomach pain is appendicitis. Parents and children will go through the checklist with a helper, but the child's actual care will be handled by a regular emergency…

This study aims to see if a one-on-one talk with a specialized nurse in a pediatric emergency room can help parents follow safe sleep rules for their babies, which could prevent sudden unexpected infant death. Researchers will enroll 100 parents of babies aged 0 to 6 months who v…

This study aims to better understand how Huntington's disease affects a person's ability to recall personal memories and imagine future events. Researchers will enroll 80 participants, including people with Huntington's disease and healthy volunteers, to complete memory tasks whi…

This study aims to understand how different pressure settings on a mechanical ventilator affect blood flow congestion in the body's veins for patients with severe lung failure (ARDS). Researchers will observe 30 critically ill patients, using ultrasound scans to measure congestio…

This study aims to understand the link between thinking skills and suicidal behavior in adolescents. Researchers will assess 100 teens aged 11-16 who are hospitalized for suicidal thoughts or attempts, measuring their ability to plan, control impulses, and adapt to situations. Th…

This study aims to better understand how spinal birth defects affect children's bladder and bowel function. Researchers will observe 210 children treated at a specific hospital to see how common these problems are and how they are currently managed. The goal is to gather informat…

This study aims to understand how an allergy to seminal fluid affects women's quality of life, including their physical, mental, and sexual health. Researchers will ask 20 women with this rare allergy to complete several questionnaires about their experiences. The goal is to see …

This study aims to understand the long-term risks to the bile ducts and pancreas in people who had surgery as infants for a congenital bowel blockage called duodenal atresia. Researchers will review the medical records of 450 patients who had this surgery in the last 20 years to …