Chemo brain hits blood cancer patients too – new study investigates
NCT ID NCT07147621
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at memory, concentration, and language problems caused by chemotherapy in people with blood cancers like leukemia and lymphoma. Researchers will compare 120 patients to their healthy relatives using tests and questionnaires before and after treatment. The goal is to understand how common these cognitive issues are and how they affect quality of life.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2026
- Expected to finish
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Oct 2027
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Participants in the patient group will be recruited from the Hematology Departments of 2 French academic centers (Angers and Brest University Hospitals). Participants in the control group will be selected among the patient's relatives (family, friends, colleagues, etc.) of the same age category (less than 5 years of difference) and with the same education level.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient group inclusion criteria: * adult patient with acute myeloid leukemia, Hodgkin's lymphoma, or non-Hodgkin's lymphoma; * patient receiving a fixed-duration first-line chemotherapy; * patient affiliated or beneficiary of a social security scheme; .signed inform consent form. * Control group inclusion criteria: * adult; * patient's relative (spouse, brother, sister, friend, etc.); * less than 5 years of difference with the patient; * same educational level (\< baccalaureate/high school degree, baccalaureate/high school degree level, 2-year university degree, \> 2-year university degree); * person affiliated or beneficiary of a social security scheme; * signed informed consent form Exclusion Criteria: * Patient group exclusion criteria: * no patient's relative for the control group; * known or suspective cognitive disorders prior to chemotherapy; * history of severe neurological or psychiatric disorders (e.g., severe depression); .previous chemotherapy; * previous brain radiotherapy; * ongoing treatments affecting cognition; * patient unable to read; * patient not speaking French; * person deprived of liberty by judicial or administrative decision; * person under forced psychiatric care; * person under legal protection measures; * person unable to express consent; .pregnant or breastfeeding woman. * Control group exclusion criteria: * known or suspected cognitive disorders; * history of severe neurological or psychiatric disorder (e.g., severe depression); .previous chemotherapy; * previous brain radiotherapy; * ongoing treatments affecting cognition; * person unable to read; * person not speaking French; * person deprived of liberty by judicial or administrative decision; * person under forced psychiatric care; * person under legal protection measures; * person unable to express consent; * pregnant or breastfeeding woman."
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University Hospital of Angers
RECRUITINGAngers, Maine et Loire, 49933, France
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