Could a light therapy save failing kidney transplants?
NCT ID NCT04870437
First seen Nov 01, 2025 · Last updated Jun 19, 2026 · Updated 27 times
Summary
This study tests a treatment called extracorporeal phototherapy (ECP) for people whose kidney transplants are failing due to chronic antibody-mediated rejection. ECP involves taking a patient's blood cells, treating them with a light-activated drug and UVA light, then returning them to the body. The goal is to calm the immune system and slow rejection. The trial will enroll 30 kidney transplant recipients to see if ECP can change certain immune cell levels and improve outcomes.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CHU Clermont Ferrand
RECRUITINGClermont-Ferrand, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU de STRASBOURG
RECRUITINGStrasbourg, France
Contact Email: •••••@•••••
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Chu Besancon
RECRUITINGBesançon, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Chu Saint Etienne
RECRUITINGSaint-Etienne, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
extracorporeal phototherapy (ECP)
What this could lead to
If it works, this could point toward a new treatment to control chronic rejection and help kidney transplants last longer.
What could go wrong
This is a small, early-phase study with only 30 participants, so results may not apply broadly. The treatment is already used for other conditions, but its effect on kidney rejection is unproven.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.