The Hospital For Sick Children

This study tested whether personalized text messages can help young adults with type 1 diabetes feel more confident managing their condition as they switch from pediatric to adult care. About 234 participants received either usual care or extra text-based support. The goal was to…

This study looked at whether giving iron supplements to children aged 1 to 3 years with low iron (but not anemia) helps their learning and development. 127 children received either iron liquid or a placebo for 4 months, plus diet advice. Researchers measured thinking and motor sk…

This study tested whether online peer support helps family caregivers of people with neuromuscular disease feel more capable and less alone. About 100 Canadian caregivers were randomly assigned to receive virtual peer support or not. The goal was to see if talking with someone wh…

This study tested whether a 3-day course of the oral steroid dexamethasone can reduce the severity of obstructive sleep apnea (OSA) in children aged 2 to 10. Ten children with moderate to severe OSA received either the drug or a placebo, and their breathing during sleep was measu…

This study looked at whether taking creatine and coenzyme Q10 supplements, along with exercise, could help children with juvenile myositis—a disease that causes muscle weakness and fatigue. Fifteen children aged 7 to 18 took part. The goal was to see if these supplements could bo…

This study tested a smartphone app and website called iCanCope with Pain for teens and young adults (ages 15-25) living with chronic pain. The program helps users track pain, sleep, mood, and activity, set goals, and learn pain management skills. Researchers checked if the progra…

This study tested whether a mindfulness-based program could help teenagers with moderate to severe obstructive sleep apnea use their CPAP machine more consistently. Thirty-seven teens aged 13-18 took part, comparing mindfulness training to online peer support. The goal was to see…

This study tested whether regularly asking children with cancer about their symptoms and linking them to specific care plans can reduce their discomfort and improve quality of life. Over 400 children aged 8-18 from 20 hospitals took part. The approach used a simple symptom checkl…

This study tested a virtual support program for people who recently started using a breathing machine at home. The goal was to see if the program could reduce emergency room visits and help caregivers feel more in control. 444 children and adults in Ontario took part, comparing t…

This study aims to develop a method to measure how the body breaks down tryptophan, an essential amino acid. Ten healthy adults aged 18-45 will take a special tracer and provide blood and urine samples. The goal is to eventually use this method to improve nutrition for preterm ba…

This study looked at whether giving pregnant mothers extra oxygen can increase oxygen levels in the brains of fetuses with congenital heart disease. Researchers used MRI and ultrasound to measure changes in 53 fetuses with different types of heart defects. The goal was to see if …

This study looked at whether giving extra oxygen to pregnant women carrying babies with a heart condition called transposition of the great arteries (TGA) can help doctors predict how well the baby will do after birth. Researchers used ultrasound and MRI to measure blood flow and…

This study looked at how different preventive treatments for moderate or severe hemophilia A affect the daily lives of boys aged 7 to 18 and their families. Researchers compared an intravenous factor replacement product with a subcutaneous non-factor product by having participant…

This study looked at whether a specific inflammatory protein, HMGB1, is higher in children with congenital heart disease and pulmonary hypertension compared to those with heart disease alone or healthy children. Researchers measured blood samples from 74 children during heart cat…