The Hospital For Sick Children

This study looks at whether a non-invasive technique called focused ultrasound can safely treat brain lesions that cause seizures in children with drug-resistant epilepsy. About 20 children aged 4-17 will be treated and followed to see if their seizures become less frequent and l…

This trial tests a program called ONLOOP that reminds adult survivors of childhood cancer to get important screening tests. These tests can catch serious late effects like heart disease or second cancers early. About 900 survivors in Ontario will be randomly assigned to use ONLOO…

This study tests whether a mechanical arm ultrasound system can detect joint damage in people with hemophilia as accurately as expert ultrasound and MRI. Eleven participants will have their joints scanned to see if the new method catches early problems that physical exams might m…

This study tests an AI tool that helps doctors decide whether babies with hydronephrosis (kidney swelling) need surgery or can be safely monitored. About 322 infants up to 24 months old will take part. Doctors first make a decision without AI, then see the AI's recommendation and…

This study tests whether a high-flow nasal cannula (HFNC) is a comfortable and effective alternative to CPAP for children with moderate-to-severe obstructive sleep apnea. About 258 children aged 2 to 18 will use one of the two devices at home for 3 months. Researchers will measur…

This study tests a smartphone app called PainCaRe that helps parents manage pain in young children (ages 2-11) with cancer. The app gives real-time advice for pain relief at home. About 40 parents will try the app for 8 weeks to see if it is easy to use and helps reduce their chi…

This study looks at whether the position of the anesthesia machine in the operating room affects how well anesthesiologists manage emergencies and perform breathing support. About 60 doctors will take part in simulated crisis scenarios with the machine placed in either an easy or…

This study looks at whether you need to eat complementary plant proteins (like rice and beans) in the same meal to get all the amino acids your body needs, or if eating them at different times during the day works just as well. Researchers will study 40 healthy young and older ad…

This study is testing a smartphone app called MedlyPeds that lets kids with heart disease send daily health updates to their doctors from home. About 30 children aged 8-18 with various heart conditions will use the app for 3 months. The goal is to see if the app is easy to use an…

This pilot study aims to see if a larger clinical trial comparing dexamethasone to a placebo for children hospitalized with orbital cellulitis can be done successfully. About 30 children and teens will take part to check if enough patients can be recruited, if the treatment can b…

This study explores whether MRI can create detailed images of the lungs and airways in children and teens with cystic fibrosis (CF) and healthy volunteers. Researchers will use computer assistance to measure airway size and shape, and repeat scans after two years to track changes…

This study compares AI-assisted video laryngoscopy to standard video laryngoscopy for placing breathing tubes in children and newborn mannequins. Forty healthcare workers with different experience levels will perform intubations to see if AI guidance speeds up the process and imp…