Sun Yat-sen University

This phase 2 trial tested a combination of two drugs—anlotinib and toripalimab—in 70 people with advanced soft-tissue sarcoma that had stopped responding to standard treatment. The goal was to see if the combo could shrink tumors or slow the disease. The study is now complete.…

This study tested whether adding a liver-directed chemotherapy infusion (HAIC) to a standard drug combo (Gemox, lenvatinib, toripalimab) helps people with advanced bile duct cancer live longer without the disease getting worse. 96 patients took part. The goal was to see if the ex…

This study looked at 200 people with advanced liver cancer whose first treatment stopped working. Researchers compared two different drug combinations to see which works better as a second treatment. The goal is to help doctors choose the best option for patients.

This early-phase trial tested a personalized cell therapy for people with advanced bone or soft tissue sarcoma that had stopped responding to standard treatment. The therapy uses the patient's own immune cells, modified to better recognize and attack cancer cells carrying a speci…

This study looked at liver cancer patients whose tumors shrank completely after non-surgical treatments like chemoembolization and immunotherapy. Researchers compared those who then had surgery to remove any remaining tissue versus those who simply watched and waited. The goal wa…

This study tested whether adding the targeted drug bevacizumab to a powerful three-drug chemotherapy regimen (FOLFOXIRI) could shrink liver tumors from colorectal cancer enough to allow surgical removal. The trial enrolled 138 people with a specific genetic mutation (RAS mutation…

This study looked at whether adding chemotherapy to radiation therapy is better than radiation alone for people with intermediate-risk nasopharyngeal carcinoma. The trial used modern intensity-modulated radiotherapy (IMRT), which is more precise than older techniques. 338 partici…

This study tested whether adding a low-dose chemotherapy pill (capecitabine) to standard hormone therapy (aromatase inhibitor) helps women with a common type of advanced breast cancer live longer without the disease getting worse. The trial involved 263 women who had not received…

This study tested a combination of two drugs (cadonilimab and lenvatinib) given before surgery to 39 people with kidney cancer that was difficult to operate on while saving the kidney. The goal was to shrink the tumor enough to allow a partial, kidney-sparing surgery instead of r…

This study tested a combination of two drugs, cadonilimab and regorafenib, in 36 adults with advanced liver cancer that had gotten worse despite prior therapy. The goal was to see if the combo could help control the cancer longer. Participants received both drugs and were monitor…

This study tested whether adding oral diabetes drugs (metformin/pioglitazone or sitagliptin) to a short-term insulin pump can improve long-term blood sugar control and help newly diagnosed type 2 diabetes patients achieve remission. 264 participants who were newly diagnosed, not …

This study tested a combination of two drugs, pamiparib and surufatinib, in 29 women with ovarian cancer that stopped responding to platinum chemotherapy and had previously taken PARP inhibitors. The goal was to see if the combo could control the cancer for at least 6 months. The…

This study tested a combination of an immunotherapy drug (anti-PD-1) and a chemotherapy drug (albumin-bound paclitaxel) in 27 people whose cervical cancer had returned or worsened after standard treatment. The goal was to see if the combination could shrink tumors and help patien…

This early-phase study tested a new dosing schedule of cetuximab combined with capecitabine as maintenance therapy for people with a specific type of metastatic colorectal cancer (KRAS/BRAF wild-type). The study involved 24 participants and aimed to find the safest dose and under…

This study tested whether adding the antibiotic moxifloxacin to standard chemotherapy improves outcomes for people with operable breast cancer. 559 participants were randomly assigned to receive either moxifloxacin or a placebo alongside their chemo. The main goal was to see if t…

This study tested a combination of two drugs, apatinib and etoposide, in 35 women with ovarian cancer that had stopped responding to platinum-based chemotherapy. The goal was to see if the combination could shrink tumors or slow disease progression. Participants took the drugs by…

This study tested a powerful three-drug combination in 46 people with a specific type of lung cancer (EGFR-mutated) that had spread to the lining of the brain and spinal cord (meningeal metastasis). The treatment used a high dose of the targeted pill furmonertinib, plus the IV dr…

This study tested whether taking anlotinib pills after initial chemotherapy can help keep advanced soft tissue sarcoma from growing. 49 adults with certain types of sarcoma took anlotinib daily. The goal was to see how long the cancer stayed stable and to check safety. Anlotinib …

This study tested whether adding an extra chemotherapy drug (capecitabine) after standard treatment helps people with advanced nasopharyngeal cancer that is likely to spread. 294 patients received either standard chemoradiotherapy alone or standard treatment plus capecitabine. Th…

This study tested a combination of an immunotherapy drug (durvalumab) and chemotherapy delivered directly to the liver (HAIC) in 30 adults with advanced liver cancer that had spread into the main portal vein. The goal was to see if the combination could improve one-year survival.…

This study reviewed medical records of 300 adults with high-risk liver cancer who received a combination of two drugs (atezolizumab and bevacizumab) plus chemotherapy directly into the liver artery. The goal was to see how well this treatment worked and how safe it was in real-wo…

This study tested a new surgical technique for esophageal cancer that avoids a large chest incision. 35 patients with early-stage cancer received this less invasive procedure. The goal was to see if it could lower complication rates while still effectively removing the cancer. Re…

This study tested an artificial intelligence platform that screens for cognitive problems like dementia by analyzing how people move their eyes. Over 1,500 participants with various cognitive conditions took part. The goal was to see if eye movement patterns could accurately dete…

This study tested a new way to find small cancer spots in neck lymph nodes of people with nasopharyngeal cancer. Researchers combined MRI scans with a special ultrasound that uses a contrast agent. They aimed to create a better rule for spotting these tiny metastases. 348 patient…

This phase 3 trial tested whether ulinastatin, a drug that blocks certain enzymes, can reduce severe mouth sores caused by chemoradiotherapy in 179 patients with advanced nasopharyngeal cancer. Patients received either standard care or ulinastatin alongside their cancer treatment…

This study tested a virtual peer agent—a friendly AI that talks with teens—to see if it can help them handle stressful life events. Fifty-five teens aged 14 to 25 used the agent for 4 weeks, having conversations about emotions, coping strategies, and support. Researchers checked …

This study looked at 252 adults having lung surgery to see if giving pain medicine in small bursts (programmed intermittent bolus) works better than a steady drip (continuous infusion). Both methods use an epidural, a common pain relief technique. The goal was to find which appro…

This study tested two Oclean sonic electric toothbrushes against a standard manual toothbrush to see which reduces extrinsic tooth stains best. Over 8 weeks, 129 adults brushed twice daily and had their stains measured using a standard index. The goal was to find out if the sonic…

This study tested whether neurotropin, a drug that may protect nerves, can reduce the nerve damage caused by oxaliplatin chemotherapy in people with stage II or III colorectal cancer. The trial included 333 participants who had surgery and were about to start chemotherapy. Resear…

This completed phase 2 study tested whether a new type of PET scan (FAPI-PET/CT) can accurately predict if rectal cancer has completely disappeared after a combination of short-course radiation, immunotherapy, and chemotherapy. Fifty-two patients with locally advanced rectal canc…

This completed study followed over 1,100 pregnant women in Guangzhou to see how their diet and nutrition during and after pregnancy relate to blood sugar problems like gestational diabetes. Researchers also tracked the children's growth, brain development, and allergies up to age…

This study looked at whether watching mukbang videos (videos of people eating large amounts of food) is linked to appetite in children with cancer who are receiving chemotherapy and radiation therapy. Researchers tracked the viewing habits and appetite of 179 children aged 3-18 t…

This study looked at 103 research articles to compare the nutrients in breast milk from mothers who gave birth early (preterm) versus full-term. The goal was to see if there are differences in energy, protein, fat, and other nutrients. This is a review of existing studies, not a …

This study looked at whether low oxygen levels after esophageal cancer surgery increase the chance of a leak where the esophagus is reconnected. Researchers reviewed records of 2,083 patients, comparing those with low oxygen to those with normal levels. The goal was to see if cor…

This study used artificial intelligence to analyze data from 7,000 people with liver cancer. The goal was to create a tool that helps doctors predict liver function, treatment outcomes, and cancer spread. The tool is designed to guide decisions about surgery, chemotherapy, and ot…

Soft tissue sarcoma is a relatively rare malignant tumor with an incidence of about 1-2/100,000. The best way to obtain evidence-based medical evidence is to participate in clinical trials with new drugs (especially targeted drugs and immunotherapy). Chidamide, an oral subtype-se…