St. Jude Children's Research Hospital

This study tested whether keeping blood pressure very tightly controlled could prevent severe bone damage (osteonecrosis) in children and young adults being treated for leukemia or lymphoma. 51 participants were randomly assigned to either intensive or standard blood pressure man…

This study tested a new antibody (hu14.18K322A) added to standard chemotherapy for 153 children with high-risk neuroblastoma, a serious childhood cancer. The goal was to see if the combination improves tumor shrinkage and delays cancer return. Results help guide future treatments…

This study looked at whether a personalized exercise plan done at home can help childhood cancer survivors who have trouble exercising due to past treatment. About 181 survivors took part. The goal was to see if the program improved their ability to exercise, heart and lung healt…

This study looked at the tiny organisms (microbes) living in the mouth and nose of 62 children with blood cancers or those getting a bone marrow transplant. Researchers wanted to see how these microbes change after chemotherapy or transplant. The goal was to learn more, not to te…

This pilot study looked at whether a WHOOP wrist monitor can reliably measure resting heart rate and heart rate variability at home in 34 adult survivors of childhood Hodgkin lymphoma who had chest radiation. Participants wore the device at home and also had in-office measurement…

This study looked at whether a special type of MRI (DW-MRI) that uses no radiation can work as well as standard scans (like CT or PET-CT) for children with bone or soft-tissue sarcomas. About 98 children participated to see if the MRI could accurately detect tumors and track how …

This study aimed to create two new tools to identify and measure stigma experienced by children with cancer and their caregivers. Researchers worked with 633 participants in the United States, Guatemala, and Jordan to develop and test these tools. The goal is to help healthcare t…

This study looked at 33 children and young adults under 24 who had COVID-19. Researchers collected samples and health information to learn how the virus affects children, what symptoms they have, and what factors might make them sicker. The goal was to gather knowledge to improve…

This study followed 94 young people with sickle cell disease as they moved from pediatric to adult medical care. Researchers tracked hospital visits, treatment adherence, and quality of life to understand what helps make this transition successful. The goal is to improve programs…

This study looked at how children who survived brain tumors interact with others. Researchers tested their thinking and social skills to find out what helps or hurts their friendships. The goal was to learn more, not to test a new treatment.

This study looked at how parents who lost a child to illness thought about hope during their child's hospice care. Researchers asked 20 parents to pick photos from that time and talk about what hope meant to them. The goal was to learn from their experiences, not to test a treatm…