St. Jude Children's Research Hospital
Clinical trials sponsored by St. Jude Children's Research Hospital, explained in plain language.
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Promising leukemia drug fails to finish trial for kids with stubborn disease
Disease control TerminatedThis study tested a drug called inotuzumab ozogamicin (Besponsa) in children and young adults with a type of leukemia (B-ALL) that still had small amounts of cancer cells after standard treatment. The goal was to see if the drug could make those leftover cells disappear. Only 5 p…
Phase: PHASE2 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated May 01, 2026 16:00 UTC
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New hope for kids after transplant: study tests safer GVHD prevention
Disease control TerminatedThis study looked at a new way to prevent severe graft-versus-host disease (GVHD) in children who had a bone marrow transplant for blood cancers. The goal was to see if stopping certain immune-suppressing drugs after day 60 could lower the risk of severe GVHD. Only 3 children too…
Phase: PHASE2 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated Apr 29, 2026 15:03 UTC
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Vitamin a and vaccines: a small study that never finished
Knowledge-focused TerminatedThis study looked at whether giving vitamin A along with the pneumonia vaccine helps children ages 1 to 4 build a stronger immune response. Only 22 healthy children took part before the study was stopped early. The goal was to measure antibody levels in the blood after vaccinatio…
Phase: PHASE1 • Sponsor: St. Jude Children's Research Hospital • Aim: Knowledge-focused
Last updated May 01, 2026 16:01 UTC
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Scientists dig into childhood brain tumors to uncover genetic secrets
Knowledge-focused TerminatedThis study looked at stored tumor samples from 139 children with brain and central nervous system tumors. The goal was to find DNA changes and biomarkers that could help doctors better understand these cancers. The research did not test a new treatment, but aimed to gather knowle…
Sponsor: St. Jude Children's Research Hospital • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:05 UTC
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Heavy periods linked to loose joints? study investigates hidden connective tissue disorders
Knowledge-focused TerminatedThis study looked at whether women and girls with heavy menstrual bleeding and severe anemia might have an undiagnosed connective tissue disorder, like hypermobile Ehlers-Danlos syndrome, which causes loose joints. Researchers compared bleeding severity and other health issues be…
Sponsor: St. Jude Children's Research Hospital • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:05 UTC