Seoul National University Bundang Hospital

This study looks at whether a special filter called oXiris helps people with septic shock and acute kidney injury who need blood filtering. The filter aims to remove harmful toxins and calm inflammation. Researchers will compare survival and recovery in 360 adults who received ei…

This study tests whether choline fenofibrate, a drug that lowers fats in the blood, can reduce plaque buildup in the neck arteries of people with type 2 diabetes and mixed high cholesterol. About 56 adults will receive either choline fenofibrate or a comparison drug (policosanol)…

This study tests whether adding a targeted radiation boost to the tumor during standard pelvic radiation helps shrink large cervical cancers more before internal radiation (brachytherapy). About 17 adults with bulky squamous cell cervical cancer will receive the extra boost. Rese…

This study compares two ways to treat H. pylori, a stomach infection that can cause ulcers. One group gets a 10-day course of four antibiotics in sequence. The other gets a 7-day treatment chosen based on lab tests of the bacteria's drug resistance. The goal is to see which appro…

This study tests whether giving a thyroid hormone pill (levothyroxine) to people with mild underactive thyroid before heart bypass surgery can lower their risk of serious heart problems like heart attack, stroke, or irregular heartbeat. About 338 adults scheduled for bypass surge…

This study looks at whether hypothyroidism caused by immune checkpoint inhibitors (a type of cancer immunotherapy) can get better after stopping the immunotherapy. Researchers want to see how many patients can safely stop taking thyroid hormone replacement (levothyroxine) and wha…

This study compares two 10-day treatment plans for Helicobacter pylori, a stomach infection that can cause ulcers. Researchers want to see if a newer drug (tegoprazan) works better than the standard treatment in South Korea, where antibiotic resistance is common. About 400 adults…

This study compares two medications, enavogliflozin and pioglitazone, when added to metformin (with or without another diabetes drug) in adults with type 2 diabetes whose blood sugar is not well controlled. The goal is to see which drug better lowers blood sugar and improves hear…

This study tests whether two common blood thinners, clopidogrel and cilostazol, can slow the buildup of plaque in the neck arteries of people with type 2 diabetes. About 120 adults with diabetes and early signs of artery thickening will take one of the two drugs for a year. The g…

This study looks at whether adding omega-3 (fish oil) to a common cholesterol-lowering statin can reduce plaque buildup in the carotid arteries of people with type 2 diabetes and high cholesterol. About 105 adults will be randomly assigned to receive either atorvastatin plus omeg…

This study looks at ways to prevent kidney damage caused by contrast dye used in CT scans. It involves 190 adults hospitalized with acute heart failure and moderate kidney problems. Participants will receive either standard IV fluids or a medication to reduce fluid buildup, and r…

This study tests a digital speech therapy app called Zenicom for people who have trouble speaking after a recent stroke. About 20 adults with aphasia will either do standard speech therapy alone or add the app for two weeks. The goal is to see if the app safely improves language …

This study tests whether an extract from the Dolichos lablab plant (EDL) can reduce stomach symptoms in adults with functional dyspepsia—a condition causing fullness, pain, or burning without a clear cause. About 100 participants will take EDL or a placebo for 12 weeks. The goal …

This study aims to identify markers in blood and tissue samples that may predict how patients with inflammatory bowel disease (IBD) respond to a type of medication called TNF-alpha inhibitors. Researchers will compare samples from 100 participants, including healthy controls and …

This study looks at how colon cancer behaves differently in younger patients compared to older ones. Researchers will track 1,400 people diagnosed with colorectal cancer to see how survival and recurrence rates vary by age, sex, and tumor biology. The goal is to better understand…

This study looks at the gut bacteria of older adults with sarcopenia (age-related muscle loss) and compares them to healthy older and young adults. The goal is to find differences that could help create probiotics to treat sarcopenia. 150 people aged 65-90 with sarcopenia will pa…

This study is testing whether mild electrical stimulation of the tongue and chin muscles can help people at risk for sleep apnea. 28 adults will receive five different stimulation frequencies in one visit. Researchers will measure changes in tongue muscle thickness, length, and s…

This study looks at whether the brain's ability to use oxygen during surgery is linked to postoperative delirium (sudden confusion) in adults aged 65 and older. Researchers will measure brain oxygen levels during laparoscopic surgery using a non-invasive forehead sensor. Particip…