Peking University People's Hospital

This study looks at how different diets affect weight and cancer outcomes in overweight or obese women with endometrial cancer who are receiving fertility-sparing therapy. Participants are randomly assigned to intermittent fasting, a low-energy balanced diet, or routine care. The…

This study tests whether adding teriflunomide to high-dose dexamethasone works better than dexamethasone alone for adults newly diagnosed with immune thrombocytopenia (ITP), a condition where the immune system destroys platelets, causing bleeding. About 132 participants will rece…

This early-phase study tests a new treatment for people with aggressive B-cell lymphoma that has come back or not responded to standard therapy. The treatment uses specially engineered immune cells (CAR-T cells) that target two proteins, CD19 and CD20, on cancer cells. The main g…

This study tests a new type of CAR T-cell therapy that uses nanobodies to target two proteins (CD19 and CD22) on leukemia cells. It is for people aged 12 to 65 with B-cell acute lymphoblastic leukemia that has come back or not responded to treatment. The goal is to see if this th…

This study tests a combination of two drugs—apatinib and liposomal irinotecan—in people with advanced osteosarcoma (bone cancer) that has spread or come back after standard treatments. The goal is to find the safest and most effective dose and see if the combo can shrink tumors o…

This study looks at whether taking barley green supplements along with a calorie-controlled diet can reduce visceral fat (the harmful fat around your organs) in people with high body fat. About 66 adults with high body fat will be split into two groups: one gets barley green plus…

This early-phase study tests whether specially engineered immune cells (CAR-T cells) can safely eliminate small amounts of leftover T-cell leukemia or lymphoma in patients who have already received a stem cell transplant. About 18 participants will receive the treatment and be mo…

This study compares two surgical approaches for people with chronic angle-closure glaucoma who also have cataracts. One surgery removes the cataract and opens the eye's drainage angle; the other adds a tiny blade to further open the drainage. The goal is to see which better lower…

This study looks at whether a medicine called hepatitis B immunoglobulin (HBIG) can help people with chronic hepatitis B stay virus-free after initial treatment. About 132 adults who have already cleared the virus with standard therapy will either receive HBIG or no extra treatme…

This study tests a procedure where a person's own skin cells are transplanted onto stable white patches caused by vitiligo. The goal is to see how well and how long the color returns. About 30 people aged 8 to 65 with stable vitiligo covering at least 5% of their body will take p…

This study is for people with breast cancer who cannot have surgery due to health reasons or choose not to for cosmetic concerns. It tests a device that uses extreme cold and heat to destroy tumors, which are then absorbed by the body. The goal is to see if this minimally invasiv…

This study looks at how well and how safely a methotrexate injection works for Chinese adults with rheumatoid arthritis (RA). It will follow 10,000 people in regular clinics, including those with additional lung or heart problems. The goal is to see if the drug helps control join…

This study tests a new treatment using specially engineered immune cells (CAR-T cells) that target a protein called CD5 on cancer cells. It is for 30 people aged 3 to 70 with T-cell acute lymphoblastic leukemia or T-cell lymphoma that has come back or not responded to standard tr…

This study is testing a daily pill called deucravacitinib in 10 adults with rare muscle inflammation diseases (idiopathic inflammatory myopathies). The goal is to see if the drug improves muscle strength, skin symptoms, and lab results over 6 months. Participants must have active…

This study tests whether a powerful immune cell therapy (CAR-T) works better than standard donor immune cells (DLI) to wipe out leftover leukemia in patients who had a stem cell transplant. About 70 people aged 3 to 80 with a certain type of leukemia and minimal residual disease …

This study tests fucoidan, a substance from brown seaweed, in 40 adults with active rheumatoid arthritis who haven't improved with standard drugs. The goal is to see if fucoidan can reduce joint pain and swelling over 12 weeks. This is an early-phase trial to gather initial evide…

This study tests whether adding a vitamin A-like drug (ATRA) to a platelet-boosting medication (romiplostim N01) works better than the platelet drug alone for cancer survivors whose platelet counts stay low after chemotherapy. About 220 adults with gynecologic, breast, or lung ca…

This study is for adults who have finished chemotherapy for gastrointestinal cancer and are in remission, but still have dangerously low platelet counts. Researchers want to see if adding a second drug (ATRA) to the standard platelet-boosting drug (romiplostim N01) works better t…

This study tests a new minimally invasive treatment that freezes and then heats breast tumors, comparing it to standard breast-conserving surgery. About 264 women aged 50+ with early-stage, hormone-positive breast cancer will be randomly assigned to one of the two treatments. The…

This study is for women with an early, hormone-sensitive type of breast cancer that has a higher chance of coming back. It tests whether a blood test (ctDNA) can identify who can safely skip chemotherapy and instead take a targeted pill (dalpiciclib) plus hormone therapy. About 3…

This study looks at whether weight management can improve tumor outcomes and metabolism in overweight or obese women with endometrial cancer who are receiving fertility-sparing treatment. About 240 participants will be split into two groups: one gets weight management support, th…

This study is testing a new radioactive tracer called [68Ga]Ga-PN-EpC1 that targets a protein (EpCAM) found on many epithelial tumors. About 30 adults with known or suspected tumors will get a PET/CT scan using this tracer before their planned biopsy or surgery. The goal is to se…

This study is testing a new type of PET scan that uses a special probe (68Ga-TOI-1) to find lung tumors more accurately. The probe targets a protein called CDH3, which is only found on cancer cells. Researchers will compare this new scan with the standard FDG-PET scan in 80 adult…

This study uses artificial intelligence to analyze abdominal CT scans that were already taken for other reasons. The goal is to estimate bone age and detect early signs of osteoporosis without needing additional tests or radiation. Researchers will include 3,000 adults to develop…

This study aims to create an artificial intelligence (AI) system that can automatically diagnose and stage osteoporosis and osteoarthritis from medical images like X-rays and MRIs. Researchers will enroll 2,000 adults to test if the AI can provide more consistent and accurate res…

This study tests if a special PET scan (FAPI-PET) and a fluorescent dye can help doctors find leftover lung cancer during surgery after standard treatment. About 200 people with stage II-IIIB non-small cell lung cancer will get the scan and dye before and during surgery. The goal…

This study tests if a special blood test that looks for MDS stem cells can better predict whether the disease will come back after a stem cell transplant. Researchers will follow 163 people with MDS who receive a transplant. The goal is to improve how doctors monitor for remainin…

This study compares two ways to take tissue samples from stomach tumors: a newer method called mucosal cutting biopsy (MCB) and the standard method using an ultrasound-guided needle (EUS-FNA). The goal is to see which method gives a more accurate diagnosis. About 96 adults with s…

This study is developing a new, non-invasive way to monitor lung cancer patients after surgery using blood tests and artificial intelligence. Researchers will analyze blood samples from 100 patients who have had surgery and chemotherapy to look for signs of cancer returning. The …

This study aims to create a prediction tool for pregnant women with aplastic anemia, a rare blood condition that raises risks for both mother and baby. Researchers will follow 300 women to identify factors that lead to complications like bleeding, preterm birth, or low birth weig…

This study follows 100 adults with acute myeloid leukemia who have had a stem cell transplant. Researchers use a highly sensitive DNA test (digital PCR) to look for tiny amounts of leukemia-related mutations in the blood at several time points during the first year after transpla…

This study looks at whether a quick drop in a blood marker called dFLC within the first week of treatment can predict a complete response in people with AL amyloidosis, a rare disease where abnormal proteins build up in organs. Researchers will follow 50 patients starting a stand…

This study looks at a part of the eye called the vitreous zonule and how it might play a role in primary angle-closure glaucoma, a condition that can damage vision. Researchers will use special 3D ultrasound imaging to examine this structure in 440 people, including those with ea…

This study looks at whether measuring leukemia stem cells can help predict if acute myeloid leukemia (AML) with MLL rearrangement will come back. Researchers will test bone marrow samples from 210 patients aged 6-60 who are receiving chemotherapy or a stem cell transplant. The go…

This study looks at whether finding leukemia stem cells in the blood and bone marrow can better predict when childhood acute myeloid leukemia will come back. About 283 children newly diagnosed with AML will be followed to see if these cells are more accurate than current tests. T…

This study looks at whether blocking light with an eye shield during general anesthesia changes how much sedative medicine is needed. About 66 adults having surgery will be randomly assigned to wear an eye shield or not. Researchers will measure drug doses, time to fall asleep, a…

This study will follow about 500 Chinese adults newly diagnosed with multiple myeloma who are starting immunotherapy as their first treatment. Researchers will collect data on which drug combinations are used and how well they work over one year, with longer follow-up for surviva…

This study tracks 6,000 people who had a stem cell transplant to learn more about serious fungal infections that can occur afterward. Researchers will collect information on diagnosis, treatment, and outcomes over five years. The goal is to find better ways to prevent and treat t…

This study follows 10,000 people who have had a stem cell transplant to see how often heart problems occur afterward. Researchers will collect medical information and track events like heart attacks, strokes, and heart failure. The goal is to better understand and manage these ri…