Peking University People's Hospital

This early-stage study tests a new treatment called IASO207 for people with B-cell blood cancers that have come back or not responded to other treatments. The main goals are to check safety and find the right dose. About 18 adults aged 18 to 75 will take part. The treatment uses …

This study tests the drug baricitinib in 28 adults who have dangerously low platelet counts after a stem cell transplant and did not improve with standard treatments. The goal is to see if baricitinib can safely raise platelet levels without needing transfusions. Participants wil…

This study tests different doses of zanubrutinib, taken with high-dose dexamethasone, in 60 adults newly diagnosed with immune thrombocytopenia (ITP). The goal is to find the safest and most effective dose to raise platelet counts and prevent bleeding. Participants will be follow…

This study tests whether the drug interferon-α can help prevent acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) from coming back in patients with a TP53 gene mutation who have already had a stem cell transplant. About 100 people aged 12-65 will receive interferon-α…

This study tests a new drug combination for people with a rare disease called AL amyloidosis, where abnormal proteins build up in organs. Participants must have a specific genetic marker (t(11;14)). They will receive Sonrotoclax plus dexamethasone, with or without another drug (d…

This study will track about 159 adults in China with relapsed/refractory multiple myeloma who are taking elranatamab as part of their regular care. Researchers want to see how well the drug controls the cancer and affects quality of life. This is an observational study, meaning n…

This study tests an experimental drug called golidocitinib in adults with immune thrombocytopenia (ITP), a condition where the immune system destroys platelets, causing bleeding risks. The trial includes 138 participants who have not responded well to standard treatments. The goa…

This study tests a personalized approach for women with hormone receptor-positive, HER2-negative early breast cancer. Participants receive a combination of targeted pills (CDK4/6 inhibitors) and hormone therapy before surgery. A blood test (ctDNA) tracks genetic changes to see if…

This study looks at two ways of giving donor immune cells after a stem cell transplant to prevent cancer from coming back in people with hard-to-treat acute myeloid leukemia or myelodysplastic syndromes. About 200 participants will be randomly assigned to receive donor cells eith…

This study tests a new way to help people with severe blunt chest trauma (like from a car crash) breathe better. It uses a non-invasive monitor (EIT) to guide a therapy that opens up the lungs and clears airways. The goal is to shorten time on a breathing machine, reduce lung inf…

This study tests a new combination of drugs (BFCA regimen) given before a stem cell transplant from a half-matched donor. It aims to improve survival and reduce treatment failure in people aged 40 to 60 with severe aplastic anemia. The study will enroll 64 participants across mul…

This study looks at whether older or frail patients with acute myeloid leukemia (AML) can safely take a shorter course of the drug venetoclax, based on their bone marrow results on Day 14, instead of the standard longer course. About 250 participants will be randomly assigned to …

This study looks at whether a pill called ivarmacitinib can help people with moderate-to-severe eczema (atopic dermatitis) who didn't get better after using other injectable medications. About 300 adults will take the pill for 16 weeks, and doctors will check if their skin rash a…

This observational study aims to develop an AI system that uses diffusion-weighted imaging (DWI) to create synthetic contrast-enhanced breast MRI images, potentially diagnosing breast cancer without injecting contrast agents. Researchers will enroll 12,000 adults who need a breas…

This study looks at whether a new blood test (mNGS) can more accurately diagnose invasive fungal lung infections in 1,000 people with blood disorders like leukemia or lymphoma. Participants will give a blood sample and be followed for 42 days. The goal is to see if this test work…

This study looks at whether the position a woman gives birth in (lying on back, upright, or on side) can help prevent stress urinary incontinence after delivery. Researchers will follow 669 first-time mothers, ages 20-35, who plan a vaginal delivery. Pelvic floor function will be…

This study tests whether acupuncture can safely reduce hot flashes in women with hormone receptor-positive breast cancer who are on hormone therapy. Sixty participants will receive either real or sham acupuncture three times a week for eight weeks, then be followed for 16 more we…

This study tests if a mild electrical stimulation applied to the ear (called taVNS) can reduce joint and muscle pain caused by aromatase inhibitors, a common hormone therapy for breast cancer. About 216 women with hormone receptor-positive breast cancer will receive either active…

This study will follow 15 people with primary antibody immunodeficiency who are receiving immunoglobulin therapy. Researchers will measure changes in specific immune cells (T and B cells) in the blood and track how many serious infections occur. The goal is to better understand h…

This study will follow 4,000 people who become critically ill after a stem cell transplant (hematopoietic cell transplantation). Researchers will collect information on their health, treatments, and outcomes while in the intensive care unit (ICU). The goal is to better understand…

This observational study looks at how a protein called irisin, released during exercise, might protect the brain and lower the risk of postoperative delirium (confusion after surgery) in older adults. Researchers will enroll 140 people aged 65 and older who are having non-heart s…

This study looks at how low body temperature during lung cancer surgery affects pain and complications afterward. About 144 adults having chest surgery with a tiny camera will have their temperature tracked continuously. The goal is to understand if staying warm during surgery he…

This study looks at 1,150 people with a type of glaucoma (primary angle-closure disease) who need a combined surgery to remove the cataract and open the eye's drainage system. The goal is to find out which patients are at risk for a rare but serious complication called ciliary bl…

This study will use the FreeStyle Libre 2, a small sensor worn on the skin, to track blood sugar changes in 120 people with rare forms of diabetes or extreme insulin problems. The goal is to find unique patterns that help doctors identify these conditions earlier and tailor treat…

This study will use a high-tech blood test (mass spectrometry) to look at different immune cells in 500 people with various autoimmune diseases and healthy volunteers. The goal is to find patterns that could help doctors screen for and diagnose these conditions earlier. No new tr…