Milton S. Hershey Medical Center
Clinical trials sponsored by Milton S. Hershey Medical Center, explained in plain language.
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Rural clinics boost HPV vaccination with simple doctor training and parent reminders
⭐️ VACCINE ⭐️ CompletedThis study tested two ways to increase HPV vaccination in rural Pennsylvania clinics. One group of clinics trained doctors to make strong vaccine recommendations and answer parents' questions. Another group added automated reminders for parents who initially said no. The goal was…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: ⭐️ VACCINE ⭐️
Last updated May 26, 2026 03:12 UTC
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VR diet coach tested for fatty liver
Disease control CompletedThis study tested a virtual reality (VR) diet program for adults with fatty liver disease. 20 participants used the VR program along with video counseling to learn about healthy eating and weight loss. The goal was to see if this approach is practical and can help people lose wei…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Disease control
Last updated May 22, 2026 14:02 UTC
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Inositol shows promise for PCOS hormone balance
Disease control CompletedThis study tested whether inositol, a natural supplement, can improve hormone levels in women with Polycystic Ovary Syndrome (PCOS). 154 women with irregular periods and high male hormones took different doses of inositol to see if it lowered testosterone and improved insulin res…
Phase: PHASE2 • Sponsor: Milton S. Hershey Medical Center • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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Berry power: black raspberry lozenges may shield Smokers' DNA
Disease control CompletedThis study looked at whether black raspberry lozenges could lower harmful DNA changes in mouth cells caused by smoking. 69 adult smokers took the lozenges for several weeks. The goal was to see if the berries could reduce damage linked to cancer risk. Results may help find a simp…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Disease control
Last updated May 18, 2026 12:03 UTC
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Can exercise coaching keep seniors safe from falls?
Prevention CompletedThis study looked at whether exercise coaching can help prevent serious fall injuries in older adults who have already had a bone fracture. Over 1,100 people aged 65 and older took part, with some getting extra exercise guidance and others receiving standard care. Researchers tra…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Prevention
Last updated May 26, 2026 03:04 UTC
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Can a malaria drug stop lupus before it starts?
Prevention CompletedThis study tested whether hydroxychloroquine, a medicine used for malaria, can slow down or prevent lupus in people who show early signs of the disease. 187 participants with mild symptoms and positive antibody tests were randomly given either the drug or a placebo. Researchers t…
Phase: PHASE2 • Sponsor: Milton S. Hershey Medical Center • Aim: Prevention
Last updated May 15, 2026 11:56 UTC
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Mindfulness may ease diabetes stress and lower blood sugar
Symptom relief CompletedThis study tested whether a 6-month online mindfulness program could help adults with type 1 or type 2 diabetes lower their blood sugar and stress. About 309 people with high stress and uncontrolled diabetes took part. Half received mindfulness training, the other half stress man…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Symptom relief
Last updated May 26, 2026 03:16 UTC
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Eye drop offers new hope for droopy eyelids after facial paralysis
Symptom relief CompletedThis study tested an FDA-approved eye drop (oxymetazoline) to treat droopy eyelids that can happen after facial paralysis. The droopiness occurs because nerves heal abnormally, causing the wrong muscles to tighten. The trial included 36 adults and measured changes in eyelid posit…
Phase: PHASE3 • Sponsor: Milton S. Hershey Medical Center • Aim: Symptom relief
Last updated May 26, 2026 03:13 UTC
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Music therapy tunes down pain and anxiety in back procedures
Symptom relief CompletedThis study looked at whether playing music during common back pain treatments (like steroid injections) can help lower patients' pain and anxiety. 30 adults with chronic lower back pain took part. Researchers measured anxiety and pain levels before and after the procedure to see …
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Symptom relief
Last updated May 26, 2026 03:10 UTC
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Which lens helps you see better after cataract surgery?
Symptom relief CompletedThis study compared two types of artificial lenses used in cataract surgery to see which one gives better vision at different distances. 80 adults with cataracts received one of two lens types. The goal was to find out if one lens provides better vision for seeing things up close…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Symptom relief
Last updated May 26, 2026 02:48 UTC
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TENS device tested for endometriosis flare pain relief
Symptom relief CompletedThis study looked at whether a TENS unit, a small device that sends gentle electrical pulses through the skin, can help reduce pain during endometriosis flare-ups. Forty women with surgically confirmed endometriosis tracked their pain, medication use, and bleeding for three month…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Symptom relief
Last updated May 15, 2026 11:57 UTC
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Angelica herb supplement put to the test in prostate cancer patients
Knowledge-focused CompletedThis early-stage study looked at the safety of a single dose of an angelica herbal supplement (AGN-Cogni.Q) in 12 men aged 40 and older with prostate cancer. Researchers checked heart health and blood tests for any side effects, and measured how the body absorbs the supplement's …
Phase: PHASE1 • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 26, 2026 03:20 UTC
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Heat may ease exercise strain for leg artery patients
Knowledge-focused CompletedThis study tested whether warming the body before exercise could lower blood pressure spikes and improve walking ability in people with peripheral artery disease (PAD). Researchers measured walking time, blood pressure, and heart rate in 33 adults with and without PAD. The goal w…
Phase: EARLY_PHASE1 • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 26, 2026 03:17 UTC
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New program aims to boost colon cancer screening in underserved communities
Knowledge-focused CompletedThis study tested a program to increase colorectal cancer screening and follow-up care in federally qualified health centers, which serve many low-income and uninsured people. The program included training for doctors, reminders for patients and providers, and help navigating car…
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 26, 2026 03:16 UTC
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Can Low-Nicotine smokes plus E-Cigs cut harm for mentally ill smokers?
Knowledge-focused CompletedThis study tested whether using very low nicotine cigarettes along with nicotine-containing e-cigarettes could reduce harmful chemicals in smokers with mental health conditions. 88 smokers took part. The main goal was to measure a cancer-related substance in urine and other marke…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 26, 2026 03:12 UTC
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Robot coach helps new docs stick the landing on tricky vein procedure
Knowledge-focused CompletedThis study looked at whether a robotic training device (DHRT or DHRT+) helps new medical residents learn how to insert central lines (a type of IV into a large vein). Over 770 residents from two medical centers used the device during their regular training. Researchers then check…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 26, 2026 03:10 UTC
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Herbal immune booster put to the test in small human study
Knowledge-focused CompletedThis study tested whether a dietary supplement made from Korean Angelica root (Cogni.Q) can increase the number of key immune cells in the blood. Fifteen healthy adults took either the supplement or a placebo to compare effects on neutrophils (which fight bacteria) and natural ki…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 26, 2026 02:48 UTC
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Can a phone app help NASH patients get fit?
Knowledge-focused CompletedThis study tested whether a mobile health exercise program called EL-FIT is practical, safe, and acceptable for people with nonalcoholic steatohepatitis (NASH), a type of liver disease. Seventeen adults with NASH took part. The main goal was to see if at least half of them would …
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 20, 2026 11:57 UTC
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Blood test could boost colorectal cancer screening in underserved groups
Knowledge-focused CompletedThis study looked at why some people avoid colorectal cancer screening and whether offering a simple blood test instead of a stool test or colonoscopy could help. Researchers worked with 297 patients from community health centers who had not completed a prior screening order. The…
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 20, 2026 11:56 UTC
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BINGO for better health: fun games aim to boost cancer awareness in black communities
Knowledge-focused CompletedThis study tested whether playing educational BINGO games could help Black adults learn about cancer and clinical trials. Fifty-four people took part in the games, which were designed to build trust and awareness. The goal was to see if this fun approach could encourage more dive…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 18, 2026 12:04 UTC
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Could a gel replace metal markers in prostate radiation?
Knowledge-focused CompletedThis study looked at whether a special gel placed near the rectum can help doctors aim radiation more accurately for prostate cancer. Seventeen men who already had the gel and small metal markers were included. The goal was to see if the gel could replace the markers for daily al…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 18, 2026 12:00 UTC
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Blood test may boost colorectal cancer screening in underserved groups
Knowledge-focused CompletedThis study aimed to understand if offering a simple blood test for colorectal cancer screening would encourage more people to get screened. Researchers surveyed 297 adults aged 45-75 who had previously avoided standard screening methods like colonoscopy or stool tests. The goal w…
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 18, 2026 11:59 UTC
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Flavored vapes may boost addiction by altering brain activity
Knowledge-focused CompletedThis study looked at whether flavor chemicals in e-cigarettes can make them more addictive by changing brain function. 36 adults who regularly use tobacco products took part. Researchers measured brain activity and puffing behavior to understand how flavors influence addiction ri…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC