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Warm baths may boost walking ability in PAD patients

NCT ID NCT03900832

Knowledge-focused Sponsor: Milton S. Hershey Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether sitting in a warm bath (38-41°C) for up to 30 minutes could reduce blood pressure spikes during exercise in 33 people with peripheral artery disease (PAD). Participants walked on a treadmill, and researchers measured walking time, blood pressure, and heart rate. The goal was to see if heat exposure makes exercise easier by calming the body's stress response.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
warm bath (water at 38-41°C)
What this could lead to
If successful, this could point toward a simple, drug-free way to improve exercise tolerance in people with PAD.
What could go wrong
This is a very early, small study (33 people) testing a short-term effect. The results may not apply to all PAD patients or lead to a lasting treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Early phase 1

The earliest testing in people: a first look at safety, in a very small group.

Participants

33 people

The number who actually took part.

Started

May 2019

Finished

Jul 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 85 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: All subjects * Capable of giving informed consent * Any race or ethnicity * Men and women age 21- 85 years (inclusive) * Fluent in written and spoken English Patients with peripheral arterial disease (PAD) * Diagnosed with PAD (i.e., ankle-brachial index below 0.9) * Fontaine stage II or less - no pain while resting * Satisfactory history and physical exam Healthy subjects * Satisfactory history and physical examination * Free of acute medical conditions Exclusion Criteria: For patients with PAD and Healthy subjects * Age \< 21 years * Pregnant or nursing women * Decisional impairment * Prisoners For patients with PAD * History of CAD with symptoms of unstable angina or myocardial infarction (\<6 months) * History of epilepsy or seizure disorders For healthy subjects • Any other chronic diseases (heart, lung, neuromuscular disease or diabetes)

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Conditions

The condition(s) this trial relates to.

Motor Activity peripheral arterial disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PAD

Contacts and locations

Locations

  • Penn State Milton S. Hershey Medical Center

    Hershey, Pennsylvania, 17033, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.